Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans
Ezzeldin, N., Elshishtawy, H., El-Borady, O., Mohamed, M. (2019). Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans. EKB Journal Management System, 65(Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry)), 3213-3220. doi: 10.21608/edj.2019.73997
Naglaa Ezzeldin; Hisham Elshishtawy; Ola El-Borady; Mona Mohamed. "Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans". EKB Journal Management System, 65, Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry), 2019, 3213-3220. doi: 10.21608/edj.2019.73997
Ezzeldin, N., Elshishtawy, H., El-Borady, O., Mohamed, M. (2019). 'Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans', EKB Journal Management System, 65(Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry)), pp. 3213-3220. doi: 10.21608/edj.2019.73997
Ezzeldin, N., Elshishtawy, H., El-Borady, O., Mohamed, M. Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans. EKB Journal Management System, 2019; 65(Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry)): 3213-3220. doi: 10.21608/edj.2019.73997

Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans

Egyptian Dental Journal
Article 15, Volume 65, Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry), October 2019, Page 3213-3220  XML PDF (985.22 K)
Document Type: Original Article
DOI: 10.21608/edj.2019.73997
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Authors
Naglaa Ezzeldin1; Hisham Elshishtawy2; Ola El-Borady3; Mona Mohamed4
1Pediatric Dentistry department, Faculty of Dentistry, October University for Modern Sciences and Arts, Cairo, Egypt
2Microbial Genetics department, Agricultural Genetic Engineering Research Institute, Agriculture Research Center, Cairo, Egypt
3Nanoscience department, Institution for Nanoscience and Nanotechnology, Kafrelsheikh University, Kafrelshikh, Egypt
4Conservative Dentistry department, Faculty of Dentistry, October University for Modern Sciences and Arts, Cairo, Egypt
Abstract
Objective: The objective of this study is to compare and evaluate the antibacterial activity of modified conventional Glass ionomer restoration (GI) with zinc oxide (ZnO-NPs) and cerium oxide Nanoparticles (CeO2-NPs) on the oral Streptococcus mutans (SM).
Materials and Methods: one hundred and five disc-shaped specimens were divided into seven groups; GI, GI incorporated with three, five and seven percent ZnO-NPs and CeO2-NPs. Antibacterial activity was assessed by counting of colony forming unit (CFU) of SM after direct contact test and 96 hours biofilm evaluation. Fourier transform infrared spectroscopy (FTIR) was used to illustrate interaction between different concentrations of Nanoparticles incorporated
with GI.
Results: Direct contact test showed a significant reduction of CFU of GI incorporated with seven percent ZnO-NPs in relation to GI (P value 0.007). Biofilm evaluation showed significant reduction of CFU of GI incorporated with three, five and seven percent ZnO-NPs and five and seven percent CeO2-NPs (P value 0.000). FTIR showed Peaks at 1405 and 1635 cm–1 related to symmetric and asymmetric vibrations of COO−, those peaks were broader and red shifted in GI incorporated with ZnO-NPs and CeO-NPs.
Conclusion: Incorporation of conventional GI with ZnO-NPs and CeO2-NPs enhance its antibacterial activity against oral SM.
Keywords
Biofilm; Nanoparticles; Streptococcus mutans; Zinc Oxide
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