ASSESSMENT OF INTERLEUKIN 6 AND HIGH SENSITIVE C-REACTIVE PROTEIN AS EARLY MARKER OF NEONATAL SEPSIS
el-shafee, M., noseir, A., abdellatif, A., khalefa, N. (2022). ASSESSMENT OF INTERLEUKIN 6 AND HIGH SENSITIVE C-REACTIVE PROTEIN AS EARLY MARKER OF NEONATAL SEPSIS. EKB Journal Management System, 28(3), 463-470. doi: 10.21608/zumj.2020.17309.1540
maram magdy el-shafee; atef ibrahem noseir; Amal mohamed abdellatif; nagla ali khalefa. "ASSESSMENT OF INTERLEUKIN 6 AND HIGH SENSITIVE C-REACTIVE PROTEIN AS EARLY MARKER OF NEONATAL SEPSIS". EKB Journal Management System, 28, 3, 2022, 463-470. doi: 10.21608/zumj.2020.17309.1540
el-shafee, M., noseir, A., abdellatif, A., khalefa, N. (2022). 'ASSESSMENT OF INTERLEUKIN 6 AND HIGH SENSITIVE C-REACTIVE PROTEIN AS EARLY MARKER OF NEONATAL SEPSIS', EKB Journal Management System, 28(3), pp. 463-470. doi: 10.21608/zumj.2020.17309.1540
el-shafee, M., noseir, A., abdellatif, A., khalefa, N. ASSESSMENT OF INTERLEUKIN 6 AND HIGH SENSITIVE C-REACTIVE PROTEIN AS EARLY MARKER OF NEONATAL SEPSIS. EKB Journal Management System, 2022; 28(3): 463-470. doi: 10.21608/zumj.2020.17309.1540

ASSESSMENT OF INTERLEUKIN 6 AND HIGH SENSITIVE C-REACTIVE PROTEIN AS EARLY MARKER OF NEONATAL SEPSIS

Zagazig University Medical Journal
Article 10, Volume 28, Issue 3, May 2022, Page 463-470  XML PDF (358.81 K)
Document Type: Original Article
DOI: 10.21608/zumj.2020.17309.1540
View on SCiNiTO View on SCiNiTO
Authors
maram magdy el-shafee email 1; atef ibrahem noseir2; Amal mohamed abdellatif3; nagla ali khalefa4
1pediatric departement,faculty of medicine,zagazig university
2pediatric depatement,faculty of medicine,zgazig university
3pediatric department fuculty of medicine zagazig university ,Egypt
4clinical pathology departement,faculty of medicine,zagazig university
Abstract
ABSTRACT
Background: Neonatal sepsis remains one of the leading causes of morbidity and mortality among term and preterm infants. Although advances in neonatal care have improved survival and reduce complication in preterm infants, sepsis still contributes significantly to mortality and morbidity among very low birth weight infants in neonatal intensive care unit (NICU), Aim and Objectives: the of the study is an Early detection of neonatal sepsis and this can be reached by assessment of validity of IL6 and High Sensitive CRP and compare between validity of IL6 and High sensitive CRP in diagnosis of neonatal sepsis, Patients and Methods: this is a case control study was conducted in Neonatal Intensive Care Unit in Zagazig university hospital during a period of 8 months from December 2018 to August 2019, the study was conducted on twenty septic neonates compared with another twenty healthy neonate without any obstetric complications, high sensitive CRP and IL6 were evaluated in all participant, Results: the results revealed that Significant area under curve with cutoffs >19.2 and >75.3,Sensitivity of HS-CRP were 96% and 95% respectively and Sensitivity of IL6 were 88.8% and 90.2% respectively, Conclusion: the IL-6 is the highly sensitive marker and CRP is the more specific marker for the identification of neonatal sepsis
Keywords
: Sepsis; NICU; CRP; IL6; Validity
Statistics
Article View: 233
PDF Download: 191