SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 6, Volume 9, Issue 2, December 1986, Page 78-91 PDF (420.32 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1986.74578 | ||||
View on SCiNiTO | ||||
Authors | ||||
A. M. Abdel-Alim1; S. A. Hussein1; H. I. El-Bitar2; R. A. Abdel-Aal2 | ||||
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
2Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||||
Abstract | ||||
Fourteen new oxamides were synthesized by amidation of ethyl N-(2-methyl-4-oxoquinazolin-3-yl) oxamate with the appropriate amines. Preliminary anticonvulsant activity of five oxamides was evaluated, Correlation of activity with structure of the test compounds is also discussed. | ||||
Statistics Article View: 59 PDF Download: 50 |
||||