SYNTHESIS OF SOME 2,7-DIAZABICYCLO {4.l.0} HEPT-3-ENE DERIVATIVES WITH ANALGESIC AND ANTICOCCIDIAL ACTIVITY | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 8, Volume 9, Issue 2, December 1986, Page 105-118 PDF (348.63 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1986.74582 | ||||
View on SCiNiTO | ||||
Authors | ||||
H. H. Farag1; A. M. Abdel-Alim1; H. Y. Hassan1; H. A. Hemaiat-Allah1; R. A. Abdel-Aal2; A. M. El-Badr3 | ||||
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
2Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||||
3Department of Parasitology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||||
Abstract | ||||
The 1,3-dipolar cycloaddition reaction of arylsulphonyl azides to 1,3-disubstituted-1,4-dihydropyridines afforded 2,7-diazabieyclo {4.1.0} hept-3-ene derivatives (III).These compounds exhibited more significant analgesic and anticoccidial activities than aspirin and sulphaguanidine respectively. | ||||
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