CLINICAL AND RADIOGRAPHIC EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS HYALOURONIC ACID VERSUS DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS PLATELET-RICH PLASMA FOR THE TREATMENT OF PERIODONTAL INTRABONY DEFECTS – A RANDOMIZED BLIND STUDY
El-Wakeel, N. (2017). CLINICAL AND RADIOGRAPHIC EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS HYALOURONIC ACID VERSUS DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS PLATELET-RICH PLASMA FOR THE TREATMENT OF PERIODONTAL INTRABONY DEFECTS – A RANDOMIZED BLIND STUDY. EKB Journal Management System, 63(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 1467-1475. doi: 10.21608/edj.2017.74726
Naglaa M. El-Wakeel. "CLINICAL AND RADIOGRAPHIC EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS HYALOURONIC ACID VERSUS DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS PLATELET-RICH PLASMA FOR THE TREATMENT OF PERIODONTAL INTRABONY DEFECTS – A RANDOMIZED BLIND STUDY". EKB Journal Management System, 63, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2017, 1467-1475. doi: 10.21608/edj.2017.74726
El-Wakeel, N. (2017). 'CLINICAL AND RADIOGRAPHIC EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS HYALOURONIC ACID VERSUS DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS PLATELET-RICH PLASMA FOR THE TREATMENT OF PERIODONTAL INTRABONY DEFECTS – A RANDOMIZED BLIND STUDY', EKB Journal Management System, 63(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 1467-1475. doi: 10.21608/edj.2017.74726
El-Wakeel, N. CLINICAL AND RADIOGRAPHIC EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS HYALOURONIC ACID VERSUS DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS PLATELET-RICH PLASMA FOR THE TREATMENT OF PERIODONTAL INTRABONY DEFECTS – A RANDOMIZED BLIND STUDY. EKB Journal Management System, 2017; 63(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 1467-1475. doi: 10.21608/edj.2017.74726

CLINICAL AND RADIOGRAPHIC EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS HYALOURONIC ACID VERSUS DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT PLUS PLATELET-RICH PLASMA FOR THE TREATMENT OF PERIODONTAL INTRABONY DEFECTS – A RANDOMIZED BLIND STUDY

Egyptian Dental Journal
Article 6, Volume 63, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), April 2017, Page 1467-1475  XML PDF (606.21 K)
Document Type: Original Article
DOI: 10.21608/edj.2017.74726
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Author
Naglaa M. El-Wakeel
Associate professor of Oral Medicine, Diagnosis, Periodontology and Radiology, Faculty of Dentistry, Al- Azhar (Girls Branch) and MSA Universities , Egypt.
Abstract
Objectives: The present study aimed to evaluate the effect of ; 1- combined demineralized freez dried bone allograft( DFDBA)plus hyaluronic acid(HA) compared to DFDBA alone, and 2) combined DFDBA/HA compared to DFDBA /PRP in treatment of periodontal infrabony defects(PIDs).
Subjects and methods:45 infrabony defects in subjects with chronic periodontitis were randomly divided into 3 groups treated with, group 1: DFDBA/HA, group 2: DFDBA/PRP and group 3: DFDBA alone. Clinical and radiographic measurements were made at baseline and 12 months after surgery. ANOVA followed by Tukey’s post hoc test were used to analyze the data.
Results: A statistically significant improvement in clinical attachment level( Cal) and pocket depth ( PD) as well as radiographic bone fill were reported in group 1 and 2 compared to DFDBA alone( p ≤ 0.05), a non significant difference was reported between group 1 and group 2 regarding clinical and radiographic parameters(p > 0.05).
Conclusion : Results of the present investigation suggests that the combination of DFDBA/HA is more effective both clinically and radiographically than DFDBA alone in treatment of PIDs and that both HA and PRP combined with DFDBA are equally effective in treatment of these defects.
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