DONOR SITE MORBIDITY AFTER HARVESTING OF BONE FROM ANTERIOR ILIAC CREST FOR MAXILLOFACIAL RECONSTRUCTION
Naguib, A., Saad, K., Bedir, R. (2017). DONOR SITE MORBIDITY AFTER HARVESTING OF BONE FROM ANTERIOR ILIAC CREST FOR MAXILLOFACIAL RECONSTRUCTION. EKB Journal Management System, 63(Issue 1 - January (Oral Surgery)), 263-269. doi: 10.21608/edj.2017.74734
Ahmed S. Naguib; Khalid A. Saad; Rafic R. Bedir. "DONOR SITE MORBIDITY AFTER HARVESTING OF BONE FROM ANTERIOR ILIAC CREST FOR MAXILLOFACIAL RECONSTRUCTION". EKB Journal Management System, 63, Issue 1 - January (Oral Surgery), 2017, 263-269. doi: 10.21608/edj.2017.74734
Naguib, A., Saad, K., Bedir, R. (2017). 'DONOR SITE MORBIDITY AFTER HARVESTING OF BONE FROM ANTERIOR ILIAC CREST FOR MAXILLOFACIAL RECONSTRUCTION', EKB Journal Management System, 63(Issue 1 - January (Oral Surgery)), pp. 263-269. doi: 10.21608/edj.2017.74734
Naguib, A., Saad, K., Bedir, R. DONOR SITE MORBIDITY AFTER HARVESTING OF BONE FROM ANTERIOR ILIAC CREST FOR MAXILLOFACIAL RECONSTRUCTION. EKB Journal Management System, 2017; 63(Issue 1 - January (Oral Surgery)): 263-269. doi: 10.21608/edj.2017.74734

DONOR SITE MORBIDITY AFTER HARVESTING OF BONE FROM ANTERIOR ILIAC CREST FOR MAXILLOFACIAL RECONSTRUCTION

Egyptian Dental Journal
Article 5, Volume 63, Issue 1 - January (Oral Surgery), January 2017, Page 263-269  XML PDF (529.51 K)
Document Type: Original Article
DOI: 10.21608/edj.2017.74734
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Authors
Ahmed S. Naguib1; Khalid A. Saad2; Rafic R. Bedir1
1Lecturer, Oral and Maxillofacial Surgery Dept., Faculty of Dentistry, Tanta University.
2Associate Professor, Oral and Maxillofacial Surgery Dept., Faculty of Dentistry, Tanta University.
Abstract
Aim of the study: The aim of the current study was to assess the vitality of autogenous bone grafts harvested from rabbits` calvaria following decontamination of the grafts using three different antimicrobial agents.
Materials and Methods: Autogenous bone grafts were harvested from the calvaria of twenty four white New Zealand male rabbits. The grafts were allowed a five minutes contact time with normal saline (Group I), 2% chlorhexidine (Group II), Clindamycine (Group III) and Oleozone gel (Group IV). The grafts were then reinserted into the previously created graft beds. Animals were sacrificed at 10 and 21 days post surgery, dual energy x-ray absorptiometry (DEXA) scans were performed for the skull of the rabbits and bone specimens were collected for histological examination.
Results: Histomorphometric analysis showed a superior results in favor of the ozone treated group represented as a significantly higher percentage of normal osteocytes and marked increase in area percentage of new bone formation. Additionally, DEXA scan revealed a significant increase in bone mineral density and bone mineral concentration of the ozone treated group compared to the other studied groups.
Conclusion: The ozone treated grafts showed a distinguished preservation of osteoblastic vitality, which may indicate a superior biocompatibility compared to chlorhexidine and clindamycin.
Keywords
Autogenous bone grafts; Decontamination; Antimicrobial agents
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