In Vivo Biocompatibility of β Tri-calicum Phosphate Versus White Portland Cement in Mandibular Bone Surgical Defect in Dogs
Mohammed, A., Saleh, R., Taiema, D., Abdel-Hady, A., Metwally, A. (2019). In Vivo Biocompatibility of β Tri-calicum Phosphate Versus White Portland Cement in Mandibular Bone Surgical Defect in Dogs. EKB Journal Management System, 65(Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 3475-3485. doi: 10.21608/edj.2019.74799
Altaib Abdel Razik Mohammed; Reda Gaber Saleh; Doaa A. Taiema; Abdel-Nasser A.A. Abdel-Hady; Asmaa, A. Metwally. "In Vivo Biocompatibility of β Tri-calicum Phosphate Versus White Portland Cement in Mandibular Bone Surgical Defect in Dogs". EKB Journal Management System, 65, Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2019, 3475-3485. doi: 10.21608/edj.2019.74799
Mohammed, A., Saleh, R., Taiema, D., Abdel-Hady, A., Metwally, A. (2019). 'In Vivo Biocompatibility of β Tri-calicum Phosphate Versus White Portland Cement in Mandibular Bone Surgical Defect in Dogs', EKB Journal Management System, 65(Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 3475-3485. doi: 10.21608/edj.2019.74799
Mohammed, A., Saleh, R., Taiema, D., Abdel-Hady, A., Metwally, A. In Vivo Biocompatibility of β Tri-calicum Phosphate Versus White Portland Cement in Mandibular Bone Surgical Defect in Dogs. EKB Journal Management System, 2019; 65(Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 3475-3485. doi: 10.21608/edj.2019.74799

In Vivo Biocompatibility of β Tri-calicum Phosphate Versus White Portland Cement in Mandibular Bone Surgical Defect in Dogs

Egyptian Dental Journal
Article 11, Volume 65, Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), October 2019, Page 3475-3485  XML PDF (2.45 MB)
Document Type: Original Article
DOI: 10.21608/edj.2019.74799
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Authors
Altaib Abdel Razik Mohammed1; Reda Gaber Saleh2; Doaa A. Taiema2; Abdel-Nasser A.A. Abdel-Hady3; Asmaa, A. Metwally4
1Departments of Oral and Maxillofacial Surgery, Faculty of Dentistry, South Valley University
2Oral Biology and Histology, Faculty of Dentistry, Tanta University
3Surgery, Anaesthesiology and Radiology and the Head of the Department, Faculty of veterinary medicine, South Valley University. Qena
4Surgery, Anaesthesiology and Radiology, Faculty of veterinary medicine, Aswan University
Abstract
Back ground: Synthetic bone substitutes have been advanced, and researches are developed to more effective biomaterials with promising ability to reconstruct lost bone structure. Tricalcium phosphate biomaterials and white Portland cement are among them. The aim of the current study is to assess the effect of β-tricalcium phosphate versus white Portland cement in surgically mandibular bone defect dogs.
Material and methods: Six adult dogs were used. The anaesthesia was conducted by iv injection of thiopental sodium 20mg/kg.b.wt. and maintained using (atropine 0.04 mg/kg b.wt., xylazine 1mg/kg.b.wt. and diazepam 1mg/kg.b.wt.in saline iv drop by drop infusion ), three critical size defects were designed at the buccal side of the mandible. The defects were 5 cm apart from each other. One defects filled with sterile white Portland cement, the middle defect filled with β-tricalcium phosphate and the later one was left empty. The dogs were euthanized at the end of 1 and 8 week postoperatively respectively. The specimens were prepared for light microscope using H&E and Masson Tri-chrome staining.
Results: The experimental sides of all periods revealed increasing the amount of new bone trabeculae extended from original bone towards the center of the defect with both white Portland cement & β-tricalcium phosphate. While, the control sides displayed few new bone trabeculae at central area and the lateral wall of the bony defects. The amount of new bone trabeculae confirmed the histological results.
Conclusion: White Portland cement is a biocompatible osteoconductive economically affordable graft material and it id more efficient than β-tricalcium phosphate.
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