SELECTIVE SPECTROPHOTOMETRIC DETERMINATION OF PROMETHAZINE HYDROCHLORIDE AND THIETHYLPERAZINE MALEATE IN PHARMACEUTICAL PREPARATIONS | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 5, Volume 8, Issue 2, December 1985, Page 70-87 PDF (453.24 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.1985.75896 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| S. R. El-Shabouri; A. F. Youssef; F. A. Mohamed; A. I. Rageh | ||||
| Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
| Abstract | ||||
| A new spectrophotometric method for the determination of promethazine HCl and thiethylperazine maleats is presented. The method is based on the interaction of each drug with benzocaine and N-bromosuccinimide at room temperature to produce a blue colour. Optimum conditions for colour development and possible interferences have been studied. The proposed method has been applied to the analysis of both drugs in pharmaceutical preparations, the results of which are in good agreement with those obtained by the official methods of B.P. and U.S.P. | ||||
|
Statistics Article View: 74 PDF Download: 138 |
||||
