Parotid MR Sialography, Can it Help in Patients with Hepatitis C Virus Related Sicca Syndrome? | ||||
| The Medical Journal of Cairo University | ||||
| Article 17, Volume 87, December, December 2019, Page 4141-4145 PDF (389.3 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2019.76714 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| AHMED A. MAHMOUD, M.D.; MOHAMMED H. KAMEL, M.D.; MEDHAT M. MADBOULY, M.D. | ||||
| The Department of Radiology, Theodor Bilharz Research Institute, Cairo, Egypt | ||||
| Abstract | ||||
| Abstract Background: The Hepatitis C Virus (HCV) related sicca syndrome occurs in association with HCV infection in a range of 4-57%. Salivary gland chronic inflammation and B cell proliferation is triggered by HCV. MR sialography is a non-invasive method for salivary glands complex duct system combined with their parenchymal evaluation through conven-tional MR T2 images and source images. Aim of Study: To identify changes in parotid magnetic resonance sialography (MR Sialography) in HCV related sicca syndrome patients. Patients and Methods: Prospective study included 64 HCV related sicca syndrome patients (38 female, 26 male, mean age 44.6±10.5 years). All patients had performed parotid MR sialography. Severity of the disease was correlated with presence or absence of vasculitis and HCV disease duration. Results: MR sialography changes were found in 25% of patients, (12/32 and 4/32 in patients with and without vasculitis, respectively). Among patients with vasculitis, those with abnormal MR sialography had longer disease duration along with more severe form of the disease. Conclusion: Amongst HCV patients with vasculitis and longer disease duration, abnormal changes are identified on MR sialography. | ||||
| Keywords | ||||
| HCV-related sicca syndrome – HCV-related vasculitis – Magnetic resonance sialography | ||||
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