Synthesis, Characterization and the Antibacterial Activity of a New Ni(II) Complex of Thiosemicarbazone Ligand. | ||||
| Research Journal of Applied Biotechnology | ||||
| Article 5, Volume 5, Issue 1, June 2019, Page 42-51 PDF (1.14 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/rjab.2019.76804 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Samar A. Aly; Ayman S. Eldourghamy   ; Mona A. Hassan
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| Department of Environmental Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City. | ||||
| Abstract | ||||
| Novel complex of Ni(II) of ligand 2-(anilinoacetyl)-N-(3-methylphenyl)hydrazine-1- carbothioamide (H2L) has been synthesized and characterized by 1HNMR, IR, elemental analyses, molar conductance, UV-visible spectra, magnetic susceptibility measurements ,thermogravimetric analysis (TGA/DTG) and X-ray differaction pattern. The result confirmed that the ligand behaved as neutral bidentate, coordination take place via carbonyl oxygen(C=O) and N(2)H groups. Nickel complex is more thermally stable than free ligand . Nickel(II) complex is mononuclear, adopt square planar geometry . The ligand and complex have been tested for their inhibitory effect on the growth of bacteria against gram-positive (Streptococcus pyogenes) and gram-negative (Escherichia coli). The result revealed that Ni(II) complex showed a higher antibacterial activity against gram positive (Streptococcus pyogenes) and gram negative (Escherichia coli) bacteria than the ligand. | ||||
| Keywords | ||||
| Ni(II)complex; IR; Thermal analysis; X-ray; Antibacterial activity | ||||
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