Bone marrow aspirate versus two bone autograft types in reconstruction of alveolar cleft: A histomorphometric analysis | ||||
| Egyptian Dental Journal | ||||
| Article 15, Volume 64, Issue 2 - April (Oral Surgery), April 2018, Page 1137-1146 PDF (1.97 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2018.76982 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Hassan Abdelghany; Hesham Fattouh | ||||
| Lecturer of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University | ||||
| Abstract | ||||
| Objectives: The aim of this study was to compare histomorphometrically between bone marrow aspirate on a collagen carrier with autogenous bone grafts harvested from two different donor sites in alveolar cleft defect repair. Materials and Methods: eighteen patients with alveoalar cleft defect were included in the study. Twelve out of eighteen patients were reconstructed with auotogenous bone graft; six patients grafted with illium bone graft and six patients grafted with chin bone graft. The remaining patients out of eighteen were reconstructed using bone marrow aspirate implanted on a collagen carrier. Six months after grafting, bone specimens from augmented alveolar ridge sites were retrieved by trephine burs for histomorphometric analysis. Results: Good consolidation of the grafts have been observed, this was demonstrated by intense osteogenesis indicating an active remodeling process. In all groups, the improvement in bone quality of the receptor site was clear with no statistical significance between the groups, however, the autografts presented better bone quality. Conclusions: From this study it was possible to conclude that quality of bone repair using autogenous bone graft is superior to bone marrow aspirate. The time needed for bone maturation is less when chin or iliac autogenous grafts have been used in comparison to the bone marrow aspirate. | ||||
| Keywords | ||||
| Alveolar cleft; stem cells; autogenous grafts; bone marrow aspirate | ||||
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