Spectrophotometric Determination of Dapsone Using Charge Transfer Complex Formation Reaction | ||||
| Egyptian Journal of Chemistry | ||||
| Article 30, Volume 63, Issue 8, August 2020, Page 3167-3177 PDF (2.03 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2020.17519.2085 | ||||
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| Authors | ||||
Mohammed S. Al-Enizzi1; OMAR ABDULHAY SHEEJ AHMAD   2; Theia’a N. Al-Sabha 2
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| 1Department of Chemistry, College of Education for Girls, Mosul University, Mosul, Iraq | ||||
| 2Chemistry Department, College of Education For Pure Science, Mosul University, Mosul, Iraq | ||||
| Abstract | ||||
| A straightforward and sensitive spectrophotometric method for the determination of Dapsone has been developed. The method is based on the charge transfer complex formation reaction of dapsone as n-donors with o-chloranil (o-CA) as π-acceptor in aqueous medium forming coloured complex with maximum absorption at 394 nm. Beer’s law was obeyed in concentration ranges of 0.125-1.25 µg/ml with molar absorptivity 1.092×105 L. mol-1.cm-1. The accuracy of the method (average recovery %) was 100.34% and precision (RSD) ≤ 3.91 %. The results show that complex is formed in ratio 1:2 with the stability constant 3.81×109 l2.mol-2. The suggested method was applied successfully to determine Dapsone in its pharmaceutical preparation. | ||||
| Keywords | ||||
| Dapsone; Charge transfer complex; o-Chloranil | ||||
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