Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study | ||||
Journal of advanced Biomedical and Pharmaceutical Sciences | ||||
Article 3, Volume 3, Issue 2, April 2020, Page 60-64 PDF (633.78 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jabps.2020.21568.1065 | ||||
View on SCiNiTO | ||||
Authors | ||||
Maha M. AlRasheed1; Lina F. Hammad2; Abeer F. Altaweel1; Alaa A. Assiri1; Albatool A. Bin Ajlan1; Rawan A. Almugbel1; Shaikha Y. Aldukhail1; Norah O. Abanmy1; Gamal A. Shazly 3, 4 | ||||
1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia | ||||
2Department of Radiological Science, College of Applied Medical Sciences, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia | ||||
3Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia | ||||
4Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University 71526, Assiut, Egypt | ||||
Abstract | ||||
Background/Aims: Maintaining skin elasticity and hardness is one way of keeping younger skin. This study investigates the topical effects of Aloe Vera (AV) alone and accompanied with Omega-3 (O-3) on skin hardness and thickness. Method: Healthy females were randomly selected and divided into two groups (15 in each group) for a double-blind controlled study. All volunteers, between 18-25 years of age, were not pregnant or suffering from any medical illness. Both groups were asked to put formulations having similar appearance on the skin of forearm for 30 days. A prepared skin formulation containing AV oil only was considered baseline. The other group was treated with AV oil and O-3 mixture. Skin elasticity and hardness were measured using Digital Durometer and Diagnostic Ultrasound System. Results: Compared to baseline, skin elasticity & hardness significantly improved at the end of the study in both AV and the combination groups. There was a slight synergistic effect of combining O-3 and AV on both elasticity and hardness. Conclusion: The study is the first of its kind exploring the possible use of AV and O-3 topically to reverse the signs of aging on skin thickness. At the end of trial period improvements in skin thickness were noticed. | ||||
Keywords | ||||
skin; Omega3; Aloe vera; pilot study | ||||
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