Efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus)
Hussein, M., Hassan, W. (2011). Efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus). EKB Journal Management System, 21(1), 59-66. doi: 10.21608/jvmr.2011.77664
M.M.A. Hussein; W. H. Hassan. "Efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus)". EKB Journal Management System, 21, 1, 2011, 59-66. doi: 10.21608/jvmr.2011.77664
Hussein, M., Hassan, W. (2011). 'Efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus)', EKB Journal Management System, 21(1), pp. 59-66. doi: 10.21608/jvmr.2011.77664
Hussein, M., Hassan, W. Efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus). EKB Journal Management System, 2011; 21(1): 59-66. doi: 10.21608/jvmr.2011.77664

Efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus)

Journal of Veterinary Medical Research
Article 10, Volume 21, Issue 1, March 2011, Page 59-66  XML PDF (346.56 K)
Document Type: Original Article
DOI: 10.21608/jvmr.2011.77664
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Authors
M.M.A. Hussein1; W. H. Hassan2
1Fish Department, Faculty of Veterinary Medicine, Beni-Suef University
2Bacteriology, Mycology, and Immunology Department, Faculty of Veterinary Medicine, Beni-Suef University.
Abstract
A study was conducted to investigate the efficacy of fosfomycin in controlling streptococcosis in Nile tilapia (Oreochromis niloticus). The minimum inhibitory concentrations (MICs) of fosfomycin against multiple S. iniae isolates showed a sensitivity range of 12.5- 25 'g/mL. The fosfomycin dose levels tested were 40, 60, and 80 mg of active ingredient per kilogram fish per day. Administration
of medicated feed started one day after infection by immersion exposure to S. iniae and continued for eight days. Survival rates of fosfomycin treated groups were 90, 100 and 96.6% with an average survival of 95. 53 %. On contrary, survival rates of infected non treated groups were 3.3%. All survivors and negative control groups showed no clinical signs, no gross pathology together with negative S. iniae re-isolation.
Keywords
Fosfomycin; controlling; streptococcosis; niloticus
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