Studies on dietary hypocholesterolemic agent in Briolers | ||||
Suez Canal Veterinary Medical Journal. SCVMJ | ||||
Article 2, Volume 18, Issue 1, June 2013, Page 13-26 PDF (445.26 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/scvmj.2013.78196 | ||||
View on SCiNiTO | ||||
Authors | ||||
E. El-Boushy1; Osama Abdalla2; Engy Risha3; Heba A.* 4; A. EL-Nagar5 | ||||
1Dept of Clinical Pathology , Fac. Vet. Med., Mansoura University. | ||||
2Dept of Clinical Pathology, Fac. Vet. Med., Suez Canal University | ||||
3Dept of Clinical Pathology, Fac. Vet. Med., Mansoura University. | ||||
4Dept of Clinical Pathology , Fac. Vet. Med., Mansoura University | ||||
5Dept. of Pathology, Fac. Vet. Med., Mansoura University | ||||
Abstract | ||||
In the present study, we evaluated and tested the hypocholesterolemic effect of statin (atorvastatin) in chickens. Thirty six (36) of one day old Cobb chicks were kept for 2 weeks for adaptation then divided into 3 equal groups each (12). Control (Gp.1) did not receive any treatment.GP-2 treated orally with 0.02% atorvastatin (0.2gm/kg ration). GP-3 treated orally with 0.05% atorvastatin ( 0.5gm/kg ration).Serum and whole blood sample were collected from all groups 2nd week and 4th week post treatment to evaluate some hematological and biochemical changes as well as immunomodulatory cytokines TNF-α, IL1β, and IL6. Oral treatment of the atorvastatin caused significant benefit results in chickens appeared in the correction of some biochemical parameters also try to stimulate cytokine response represents in TNF-α, IL1β, and IL6. From the present work, it could be concluded that statin (atorvastatin) has potent hypocholesterolemic effect, this appear in the correction with hematological, biochemical and immunological results. | ||||
Keywords | ||||
dietary hypocholesterolemic agent; Briolers | ||||
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