UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST | ||||
| Sinai Journal of Applied Sciences | ||||
| Article 13, Volume 6, Issue 2, August 2017, Page 213-222 PDF (559.08 K) | ||||
| DOI: 10.21608/sinjas.2017.78787 | ||||
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| Authors | ||||
Hend S. AbdElRady  ; Mohamed A.M. AbdElReheim; Ibrahim S. AbdelHafiz
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| Dept. Chem., Fac. Sci, Arish Univ., Egypt. | ||||
| Abstract | ||||
| Many heterocyclic compounds were prepared from the reaction of 2-imino-6-phenyl-2,3-dihydropyrimidin-4(5H)-one 4 with some bifunctional nucleophiles and electrophiles reagents under mild conditions .The structure of the synthesized compounds were established via their elemental and spectral analysis. Some of the products were also screened in vitro for their biological activity. | ||||
| Keywords | ||||
| Iminopyrimidine; pyrazolopyrimidin; dihydropyrimidin; dihydropyridine carbonitrile; pyrimidin-6-ylformimidate | ||||
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