Serum Lactate/Albumin Ratio as a Predictor Of Morbidity and Mortality In Patients with Severe Sepsis and Septic Shock | ||||
Benha Medical Journal | ||||
Article 7, Volume 37, Issue 1, May 2020, Page 220-228 PDF (857.81 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bmfj.2020.86205 | ||||
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Authors | ||||
Essam Makram1; Mohamed Ibrahim2; Ahmed Abdel Rahman1; Karim aboraya* 1 | ||||
1Department of Anaesthesia and Intensive Care, Benha Faculty of Medicine, Benha University | ||||
2department of nephrology and Internal medicine , Faculty of Medicine – Benha University, | ||||
Abstract | ||||
Background: Severe sepsis is common and frequently fatal and represents a significant health care burden. Sepsis is a syndrome of physiologic, pathologic, and biochemical abnormalities induced by infection. Aim of the work: This study examines the ability of serum lactate/albumin ratio to predict outcome regarding organ dysfunction and mortality in severe sepsis and septic shock. Materials and Methods: It is a prospective observational study conducted on 50 patients with severe sepsis and septic shock according to the (SCCM/ESICM/ACCP/ATS/SIS) International Sepsis Definitions Conference 2001 and fifty healthy age matched individuals as a control group. Results: Lactate/albumin ratio was higher on day 0 and 1 in the study group than in control group (p value <0.001). Also, it was significantly higher in patients that needed mechanical ventilation than patients who didn’t (p value p valuep value<0.001).Conclusion: Lactate/albumin ratio is a reliable biomarker for prediction of outcome as regards organ dysfunction and mortality in patients with severe sepsis and septic shock. | ||||
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