IMPACT OF NON-SURGICAL PERIODONTAL THERAPY ON VISFATIN LEVEL IN GINGIVAL CREVICULAR FLUID OF TYPE II DIABETIC PATIENTS WITH PERIODONTITIS
Shalaby, H., Makaky, Y. (2020). IMPACT OF NON-SURGICAL PERIODONTAL THERAPY ON VISFATIN LEVEL IN GINGIVAL CREVICULAR FLUID OF TYPE II DIABETIC PATIENTS WITH PERIODONTITIS. EKB Journal Management System, 66(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 1025-1034. doi: 10.21608/edj.2020.27020.1094
Hany Kamel Shalaby; Yasser Makaky. "IMPACT OF NON-SURGICAL PERIODONTAL THERAPY ON VISFATIN LEVEL IN GINGIVAL CREVICULAR FLUID OF TYPE II DIABETIC PATIENTS WITH PERIODONTITIS". EKB Journal Management System, 66, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2020, 1025-1034. doi: 10.21608/edj.2020.27020.1094
Shalaby, H., Makaky, Y. (2020). 'IMPACT OF NON-SURGICAL PERIODONTAL THERAPY ON VISFATIN LEVEL IN GINGIVAL CREVICULAR FLUID OF TYPE II DIABETIC PATIENTS WITH PERIODONTITIS', EKB Journal Management System, 66(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 1025-1034. doi: 10.21608/edj.2020.27020.1094
Shalaby, H., Makaky, Y. IMPACT OF NON-SURGICAL PERIODONTAL THERAPY ON VISFATIN LEVEL IN GINGIVAL CREVICULAR FLUID OF TYPE II DIABETIC PATIENTS WITH PERIODONTITIS. EKB Journal Management System, 2020; 66(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 1025-1034. doi: 10.21608/edj.2020.27020.1094

IMPACT OF NON-SURGICAL PERIODONTAL THERAPY ON VISFATIN LEVEL IN GINGIVAL CREVICULAR FLUID OF TYPE II DIABETIC PATIENTS WITH PERIODONTITIS

Egyptian Dental Journal
Article 8, Volume 66, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), April 2020, Page 1025-1034  XML PDF (358.28 K)
Document Type: Original Article
DOI: 10.21608/edj.2020.27020.1094
View on SCiNiTO View on SCiNiTO
Authors
Hany Kamel Shalaby email orcid 1; Yasser Makakyorcid 2
1Oral medicine and Periodontology, and Oral Diagnosis,Faculty of Dentistry,Suez Canal University
2Oral Medicine, periodontology department, Faculty of Dentistry, Tanta university
Abstract
ckground: Visfatin was reported to exert various pro-inflammatory function. The present
study aims to evaluate the level of visfatin in gingival crevicular fluid (GCF) and assess this
relationship in individuals with diabetes mellitus type 2 (T2DM) and periodontitis (P) before and
following nonsurgical periodontal therapy (NSPT).
Patients and methods: Forty-five subjects were enrolled in this study and equally divided into
three groups, group 1: healthy participants, group 2: patients with diabetes mellitus (T2DM) and
periodontitis and group 3: patients with periodontitis only. Clinical parameters were recorded at
baseline and after NSPT at 1, 3 and 6 months, visfatin levels were also assessed at the same time
intervals using enzyme-linked immunosorbent assay.
Results: GCF visfatin level at baseline showed a significantly lower concentration in healthy
participants than in patients with periodontitis and T2DM and those with periodontitis only. A
significant reduction in GCF visfatin level was observed in groups 2 and 3 following NSPT at 1, 3
and 6 months.
Conclusion: The non-surgical periodontal therapy can significantly reduce GCF visfatin levels
in patients with T2DM and periodontitis and those with only periodontitis. Furthermore, visfatin
may be suggested as an inflammatory marker for periodontitis.
Keywords
Periodontitis; Visfatin; Gingival crevicular fluid; Diabetes mellitus; Nonsurgical periodontal therapy
Statistics
Article View: 181
PDF Download: 274