Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome
Mehasen, M., Farid, E., Maged, A., Farid, A. (2020). Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome. EKB Journal Management System, 1(1), 91-105. doi: 10.21608/ejmr.2020.89074
Mohamed Nagi Mehasen; Eman Zein Elabdeen Farid; Ahmed Maged; Azhar Farid. "Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome". EKB Journal Management System, 1, 1, 2020, 91-105. doi: 10.21608/ejmr.2020.89074
Mehasen, M., Farid, E., Maged, A., Farid, A. (2020). 'Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome', EKB Journal Management System, 1(1), pp. 91-105. doi: 10.21608/ejmr.2020.89074
Mehasen, M., Farid, E., Maged, A., Farid, A. Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome. EKB Journal Management System, 2020; 1(1): 91-105. doi: 10.21608/ejmr.2020.89074

Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome

Egyptian Journal of Medical Research
Article 8, Volume 1, Issue 1, January 2020, Page 91-105  XML PDF (265.1 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2020.89074
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Authors
Mohamed Nagi Mehasen1; Eman Zein Elabdeen Farid2; Ahmed Maged2; Azhar Farid* 2
1Obstetrics and Gynecology department, Faculty of Medicine, Cairo University, Egypt
2Obstetrics and Gynecology department, Faculty of Medicine, Beni-Suef University, Egypt
Abstract
The goal of this study is to assess the effectiveness of phytoestrogen with clomiphene citrate for ovulation induction in women with polycystic ovarian syndrome to overcome the antiestrogenic effect of clomiphene citrate on endometrium, were randomly grouped into two groups, 50 in each group. Group 1: receiving CC 100 mg twice daily from third day of cycle for five days and group 2:  receiving CC from 3rd of cycle for 5 days plus phytoestrogen (Klimadynon(®), Bionorica, Neumarkt i.d.OBf., Germany)  (20mg of cimifuga racemosa from day 1to12). Women receiving CC plus phytoestrogen have an increase number of dominant follicles, endometrial thickness with an improvement of both ovulation rate and pregnancy rate.
Keywords
Cimicifuga; clomiphene citrate; endometrial thickness; induction; phytoestrogens
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