EFFECT OF VARIOUS VEHICLES ON THE UNIFORMITY OF DRUG CONTENTS OF DIRECTLY COMPRESSED CHLORAMPHENICOL TABLETS | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 1, Volume 7, Issue 1, June 1984, Page 1-14 PDF (455.26 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1984.89514 | ||||
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Authors | ||||
A. E. Aboutaleb; S. E. Saleh | ||||
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
Abstract | ||||
Chloramphenicol tablets were prepared using various concentrations of directly compressible vehicles. It was found that Avicel and STA-Rx produced suitable Chloramphenicol tablets which comply with B.P. requirements. On the other hand Sugartab, Anhydrous lactose, Emcompress and Celutab gave rise to tablets with long disintegration time. It was found also that all the batches were uniform with regard to their drug contents except for those tablets containing different concentrations of Sugartab. This may be due the difference in the physical properties between Chloramphenicol and Sugartab powders. | ||||
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