SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW SALICYLIC ACID DERIVATIVES CONTAINING A QUINAZOLIN-4-ONE MOIETY | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 15, Volume 7, Issue 1, June 1984, Page 224-236 PDF (496.09 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1984.89572 | ||||
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Authors | ||||
M. A. Abd-Alla1; A. S. Yanni1; Sh. H. Ahmed2; M. H. Abdel-Raheam3 | ||||
1Department of Chemistry, Facu1ty of Science, Assiut University, Assiut, Egypt | ||||
2Department of Microbiology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||||
3Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt | ||||
Abstract | ||||
A new series of salicylic acid derivatives of the general formula (IV) was prepared through the interaction of substituted 2-aryl-3-(haloformylalkyl)-3,4-dihydroquinazolin-4-one (III) with salicylic acid, methyl salicylate and sodium salicylate. The biological activities of these compounds such as antibacteria1, analgesic and antipyretic were determined. | ||||
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