INTERPLAY BETWEEN VITAMIN D STATUS AND ANTIVIRAL THERAPY AMONG CHRONIC HEPATITIS C EGYPTIAN PATIENTS
ABD ELALIM, M., ZAKY, D., MOTAWAE, I., MOHAMED, N., NAGIB, A. (2015). INTERPLAY BETWEEN VITAMIN D STATUS AND ANTIVIRAL THERAPY AMONG CHRONIC HEPATITIS C EGYPTIAN PATIENTS. EKB Journal Management System, 45(1), 17-22. doi: 10.21608/jesp.2015.89679
MOUSTAFA HAMED ABD ELALIM; DOAA ZAKARIA ZAKY; IBRAHIM ABD EL GHANY MOTAWAE; NESREEN A MOHAMED; ADLY NABIH NAGIB. "INTERPLAY BETWEEN VITAMIN D STATUS AND ANTIVIRAL THERAPY AMONG CHRONIC HEPATITIS C EGYPTIAN PATIENTS". EKB Journal Management System, 45, 1, 2015, 17-22. doi: 10.21608/jesp.2015.89679
ABD ELALIM, M., ZAKY, D., MOTAWAE, I., MOHAMED, N., NAGIB, A. (2015). 'INTERPLAY BETWEEN VITAMIN D STATUS AND ANTIVIRAL THERAPY AMONG CHRONIC HEPATITIS C EGYPTIAN PATIENTS', EKB Journal Management System, 45(1), pp. 17-22. doi: 10.21608/jesp.2015.89679
ABD ELALIM, M., ZAKY, D., MOTAWAE, I., MOHAMED, N., NAGIB, A. INTERPLAY BETWEEN VITAMIN D STATUS AND ANTIVIRAL THERAPY AMONG CHRONIC HEPATITIS C EGYPTIAN PATIENTS. EKB Journal Management System, 2015; 45(1): 17-22. doi: 10.21608/jesp.2015.89679

INTERPLAY BETWEEN VITAMIN D STATUS AND ANTIVIRAL THERAPY AMONG CHRONIC HEPATITIS C EGYPTIAN PATIENTS

Journal of the Egyptian Society of Parasitology
Article 3, Volume 45, Issue 1, April 2015, Page 17-22  XML PDF (161.34 K)
Document Type: Original Article
DOI: 10.21608/jesp.2015.89679
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Authors
MOUSTAFA HAMED ABD ELALIM1; DOAA ZAKARIA ZAKY1; IBRAHIM ABD EL GHANY MOTAWAE2; NESREEN A MOHAMED3; ADLY NABIH NAGIB
1Department of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
2Department of Internal Medicine, Faculty of Medicine, El-Menia University, El-Menia, Egypt.
3Department of Clinical Pathology, Faculty of Medicine,
Abstract
Vitamin D has been shown to play an important immunomodulatory role; deficiency of vitamin D has been recently associated to the lack of response to antiviral therapy in chronic hepatitis C patients. This study evaluated the interrelationship between serum level of vitamin D and early response to antiviral therapy in Egyptian patients with chronic HCV infection. A total of 45 patients with chronic HCV infection who received antiviral treatment (Pegylated
interferon and Ribavirin), their vitamin D serum level was assessed once at the start of treatment and 12 weeks later, when the EVR was determine by Quantitative HCV-RNA by PCR. The results showed that vitamin D status has no correlation with viral load and hepatitis activity by biopsy and without significant association between vitamin D deficiency and the antiviral therapy response. However, there was significance improvement in level of vitamin D after 12 weeks of receiving the antiviral therapy of HCV.
Keywords
Egypt; Chronic Hepatitis C Patients; Vitamin D; Antiviral Therapy
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