Urinary Retinol Binding Protein (RBP) Level as an early Biomarker of Diabetic Nephropathy in type 2 Diabetic Patients
Abdallah, N., Kamel, M., Abdelaziz, A., Abd Elkareem, R. (2020). Urinary Retinol Binding Protein (RBP) Level as an early Biomarker of Diabetic Nephropathy in type 2 Diabetic Patients. EKB Journal Management System, 1(2), 49-60. doi: 10.21608/ejmr.2020.90106
Nilly Helmy Abdallah; Mahmoud Farid Kamel; Abdelrahman Abdelaziz; Rehab Muhammad Abd Elkareem. "Urinary Retinol Binding Protein (RBP) Level as an early Biomarker of Diabetic Nephropathy in type 2 Diabetic Patients". EKB Journal Management System, 1, 2, 2020, 49-60. doi: 10.21608/ejmr.2020.90106
Abdallah, N., Kamel, M., Abdelaziz, A., Abd Elkareem, R. (2020). 'Urinary Retinol Binding Protein (RBP) Level as an early Biomarker of Diabetic Nephropathy in type 2 Diabetic Patients', EKB Journal Management System, 1(2), pp. 49-60. doi: 10.21608/ejmr.2020.90106
Abdallah, N., Kamel, M., Abdelaziz, A., Abd Elkareem, R. Urinary Retinol Binding Protein (RBP) Level as an early Biomarker of Diabetic Nephropathy in type 2 Diabetic Patients. EKB Journal Management System, 2020; 1(2): 49-60. doi: 10.21608/ejmr.2020.90106

Urinary Retinol Binding Protein (RBP) Level as an early Biomarker of Diabetic Nephropathy in type 2 Diabetic Patients

Egyptian Journal of Medical Research
Article 5, Volume 1, Issue 2, June 2020, Page 49-60  XML PDF (867 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2020.90106
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Authors
Nilly Helmy Abdallah1; Mahmoud Farid Kamel1; Abdelrahman Abdelaziz* 2; Rehab Muhammad Abd Elkareem3
1Internal Medicine department, Faculty of Medicine, Beni-Suef University, Egypt.
2Internal Medicine department, Faculty of Medicine, Beni-Suef University, Egypt
3Clinical Pathology department, Faculty of Medicine, Beni-Suef University, Egypt.
Abstract
Background:Diabetes mellitus continues to be an important clinical problem throughout the world In 2014, 8.5% of adults aged 18 years and older had diabetes. In 2015, diabetes was the direct cause of 1.6 million deaths. Objectives:To investigate the role of retinol binding protein (RBP) in the early stage of diabetic nephropathy, in patients with type 2 diabetes mellitus (T2DM). Methods: This cross-sectional observational study recruited patients with longstanding T2DM and healthy control subjects. Patients with T2DM were further stratified based on their urine albumin–creatinine ratio (UACR). Urinary concentrations of RBP were determined using an enzyme-linked immunosorbent assay.
Keywords
Retinol; Diabetic Nephropathy; Albuminuria biomarker; RBP
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