HELMINTH PARASITIC INFECTIONS OF THE CENTRAL NERVOUS SYSTEM: A DIAGNOSTIC APPROACH
OTHMAN, A., BRUSCHI, F., GANNA, A. (2014). HELMINTH PARASITIC INFECTIONS OF THE CENTRAL NERVOUS SYSTEM: A DIAGNOSTIC APPROACH. EKB Journal Management System, 44(1), 55-70. doi: 10.21608/jesp.2014.90704
AHMAD A. OTHMAN; FABRIZIO BRUSCHI; AHMED A. GANNA. "HELMINTH PARASITIC INFECTIONS OF THE CENTRAL NERVOUS SYSTEM: A DIAGNOSTIC APPROACH". EKB Journal Management System, 44, 1, 2014, 55-70. doi: 10.21608/jesp.2014.90704
OTHMAN, A., BRUSCHI, F., GANNA, A. (2014). 'HELMINTH PARASITIC INFECTIONS OF THE CENTRAL NERVOUS SYSTEM: A DIAGNOSTIC APPROACH', EKB Journal Management System, 44(1), pp. 55-70. doi: 10.21608/jesp.2014.90704
OTHMAN, A., BRUSCHI, F., GANNA, A. HELMINTH PARASITIC INFECTIONS OF THE CENTRAL NERVOUS SYSTEM: A DIAGNOSTIC APPROACH. EKB Journal Management System, 2014; 44(1): 55-70. doi: 10.21608/jesp.2014.90704

HELMINTH PARASITIC INFECTIONS OF THE CENTRAL NERVOUS SYSTEM: A DIAGNOSTIC APPROACH

Journal of the Egyptian Society of Parasitology
Article 7, Volume 44, Issue 1, April 2014, Page 55-70  XML PDF (327.57 K)
Document Type: Original Article
DOI: 10.21608/jesp.2014.90704
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Authors
AHMAD A. OTHMAN1; FABRIZIO BRUSCHI2; AHMED A. GANNA3
1Department of Medical Parasitology, Faculty of Medicine, Tanta University, Egypt.
2Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
3Department of Neurosurgery, Faculty of Medicine, Tanta University, Egypt.
Abstract
Helminth parasitic infections of the central nervous system (CNS) occur worldwide with high prevalence in tropical and subtropical countries. Clinical evaluation of patients is mandatory, and it is convenient to group the clinical manifestations into syndromes: for example space-occupying lesions, meningitis, and encephalitis. The history should focus on residence or travel to endemic areas, diet, activities, intercurrent medical conditions, and associated clinical clues. Direct parasitological diagnosis can be reached by cerebrospinal fluid and cerebral tissue examination either by microscopy, culture, or immunological techniques. Immunodiagnosis by detection of parasite antibodies or antigens in serum could
provide indirect evidence of parasitic infections. In addition, various imaging and radiological techniques e.g., computed tomography (CT) scan and magnetic resonance imaging (MRI) complement the diagnostic work-up of CNS diseases. Finally, the helminthic CNS infections of global impact, such as schistosomiasis, neurotoxocariasis, Strongyloides infection,
neurotrichinosis, neurocysticercosis, and echinococcosis will be briefly discussed as regards the principal clinical and diagnostic features.
Keywords
helminth parasitic infection; Central nervous system; Diagnosis; CSF; neuroschistosomiasis; neurocysticercosis
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