Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
Hussein, S., Ibrahim, A., Noseer, E., Semieka, M. (2020). Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs. EKB Journal Management System, 3(2), 25-37. doi: 10.21608/svu.2020.29353.1051
Shereen Hussein; Ahmed Ibrahim; Enas Noseer; Mohamed Semieka. "Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs". EKB Journal Management System, 3, 2, 2020, 25-37. doi: 10.21608/svu.2020.29353.1051
Hussein, S., Ibrahim, A., Noseer, E., Semieka, M. (2020). 'Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs', EKB Journal Management System, 3(2), pp. 25-37. doi: 10.21608/svu.2020.29353.1051
Hussein, S., Ibrahim, A., Noseer, E., Semieka, M. Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs. EKB Journal Management System, 2020; 3(2): 25-37. doi: 10.21608/svu.2020.29353.1051

Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs

SVU-International Journal of Veterinary Sciences
Article 1, Volume 3, Issue 2 - Serial Number 6, December 2020, Page 25-37  XML PDF (379.77 K)
Document Type: Research article
DOI: 10.21608/svu.2020.29353.1051
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Authors
Shereen Hussein1; Ahmed Ibrahim email 2; Enas Noseer3; Mohamed Semieka4
1MVS of Surgery, Anesthesiology, and Radiology, Faculty of Vetrinary Medicine, Assiut University, Assiut, Egypt.
2Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
3Department of Biochemistry, Faculty of Vetrinary Medicine, Aswan University, Sahary city, Aswan 81528, Egypt.
4Department of Surgery, Anesthesiology, and Radiology, Faculty of Vetrinary Medicine, Assiut University, Assiut 71526, Egypt.
Abstract
The present study aimed to evaluate intramuscular xylazine HCl 2% as an anesthetic for laparogastrotomy in dogs at different doses. Twenty-seven dogs were divided randomly and equally into three groups; group A received 4 mg/kg, group B, received 8 mg/kg, and group C received 14 mg/kg. Anesthetic indices, effect on physiological parameters, blood gases, and biochemical parameters were recorded. The onset was 4.00 ± 0.00, 3.50 ± 0.33, and 5.00 ± 0.33 min, and the duration was 18.00 ± 2.50, 21.00 ± 7.20, and 28.00 ± 4.30 min in the groups A, B, and C, respectively. Pedal reflex was absent in groups A and B from 5 - 30 min post-injection. Palpebral reflex was absent in all groups from 20 - 30 min post-injection. All dogs recorded a non-significant decrease in the rectal temperature, but a significant decrease in respiratory and heart rates. There was a significant increase in the PvCO2 level and significant hyperglycemia in all dogs. Dogs in groups B and C exhibited a significant decrease in PvO2. There was a significant decrease in the serum cortisol level in the group B. Creatinine level recorded non-significant decrease in the group A, while there was a non-significant increase in the group B. There was non-significant decrease in GGT levels in the groups A and C. Xylazine at dose of 14 mg/kg established a satisfactory stable anesthesia that was enough to conduct laparogastrotomy in dogs.
Keywords
xylazine; dogs; anesthesia; blood gases; biochemical parameters
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