ADJUNCTIVE USE OF HYALURONIC ACID WITH SCALING & ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS WITH DIABETES MELLITUS TYPE 2: A RANDOMIZED CONTROLLED TRIAL
Madkour, G., EL Refaie, I., Mostafa, B. (2018). ADJUNCTIVE USE OF HYALURONIC ACID WITH SCALING & ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS WITH DIABETES MELLITUS TYPE 2: A RANDOMIZED CONTROLLED TRIAL. EKB Journal Management System, 64(Issue 4 - October (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics)), 4057-4065. doi: 10.21608/edj.2018.91765
Gihane Gharib Madkour; Ibrahim EL Refaie; Basma Mostafa. "ADJUNCTIVE USE OF HYALURONIC ACID WITH SCALING & ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS WITH DIABETES MELLITUS TYPE 2: A RANDOMIZED CONTROLLED TRIAL". EKB Journal Management System, 64, Issue 4 - October (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics), 2018, 4057-4065. doi: 10.21608/edj.2018.91765
Madkour, G., EL Refaie, I., Mostafa, B. (2018). 'ADJUNCTIVE USE OF HYALURONIC ACID WITH SCALING & ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS WITH DIABETES MELLITUS TYPE 2: A RANDOMIZED CONTROLLED TRIAL', EKB Journal Management System, 64(Issue 4 - October (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics)), pp. 4057-4065. doi: 10.21608/edj.2018.91765
Madkour, G., EL Refaie, I., Mostafa, B. ADJUNCTIVE USE OF HYALURONIC ACID WITH SCALING & ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS WITH DIABETES MELLITUS TYPE 2: A RANDOMIZED CONTROLLED TRIAL. EKB Journal Management System, 2018; 64(Issue 4 - October (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics)): 4057-4065. doi: 10.21608/edj.2018.91765

ADJUNCTIVE USE OF HYALURONIC ACID WITH SCALING & ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS WITH DIABETES MELLITUS TYPE 2: A RANDOMIZED CONTROLLED TRIAL

Egyptian Dental Journal
Article 56, Volume 64, Issue 4 - October (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics), October 2018, Page 4057-4065  XML PDF (269.75 K)
Document Type: Original Article
DOI: 10.21608/edj.2018.91765
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Authors
Gihane Gharib Madkour1; Ibrahim EL Refaie2; Basma Mostafa3
1Associate Professor, Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University - Egypt
2Lecturer, Oral Medicine & Periodontology Department, Faculty of Dentistry, Cairo University - Egypt
3Associate Professor, Surgery and Oral Medicine Dep., Oral and Dental Research Division, National Research Centre, Cairo - Egypt
Abstract
Objective: The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling & root planing (SRP) in patients with chronic periodontitis & diabetes mellitus type 2.
Subjects &Methods: Thirty subjects with chronic periodontitis & diabetes mellitus type 2 were included in this randomized clinical trial. These subjects were randomly allocated into test & control equal groups. The test group comprised fifteen patients who received SRP with subgingival application of Hyaluronic acid as an adjunct. The control group included fifteen patients who received SRP alone. Plaque index (PI), gingival index (GI), probing depth (PD) & clinical attachment level (CAL) were measured & documented at baseline, 6 weeks & 12 weeks intervals.
Results: A statistically significant clinical improvement in all clinical parameters was shown in the test & control groups after SRP, 6 weeks & 12 weeks follow up intervals (p≤0.05). Statistically significant better results were observed in the test group, compared to control group, in all periodontal parameters, except PI, at 6 weeks and 12 weeks (P≤0.05).
Conclusion: Adjunctive use of Hyaluronic acid with SRP in the treatment of chronic periodontitis patients with diabetes mellitus type 2 offers superior clinical results compared to SRP alone.
Keywords
Hyaluronic acid; chronic periodontitis; scaling & root planning; diabetes mellitus type 2
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