Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions
adnan, S., J- Al-Adilee, K., A-Abedalrazaq, K. (2020). Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions. EKB Journal Management System, 63(12), 4749-4756. doi: 10.21608/ejchem.2020.23312.2438
shaimaa adnan; Khalid J- Al-Adilee; Khamis A-Abedalrazaq. "Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions". EKB Journal Management System, 63, 12, 2020, 4749-4756. doi: 10.21608/ejchem.2020.23312.2438
adnan, S., J- Al-Adilee, K., A-Abedalrazaq, K. (2020). 'Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions', EKB Journal Management System, 63(12), pp. 4749-4756. doi: 10.21608/ejchem.2020.23312.2438
adnan, S., J- Al-Adilee, K., A-Abedalrazaq, K. Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions. EKB Journal Management System, 2020; 63(12): 4749-4756. doi: 10.21608/ejchem.2020.23312.2438

Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions

Egyptian Journal of Chemistry
Article 8, Volume 63, Issue 12, December 2020, Page 4749-4756  XML PDF (1.59 MB)
Document Type: Review Articles
DOI: 10.21608/ejchem.2020.23312.2438
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Authors
shaimaa adnan email 1; Khalid J- Al-Adilee2; Khamis A-Abedalrazaq3
1university of Al-Qadisiyah
2college of Education , university of Al-Qadisiyah
3Universty of Al-Anbar
Abstract
A novel azo schiff base dye (L) has been Synthesized a reaction of 5- [ 2-(5-nitro thiazolyl)azo] -2-amino -4-methyl pyridine (NTAPy) with 4-chloro benzaldehyde in alkaline solution . Anew series of complexes with Ag(I) ,Au(III) and Pt(IV) ions was Prepared forming chelate complexes . The structure of azo schiff base ligand and its metal complexes were characterized by different spectral technique such as1H-NMR, 13C-NMR, mass spectrum , FT-IR, electronic Spectra , C-H.N.S analysis , magnetic susceptibility ,atomic absorption and molar conductivity .The analytical data suggests the mole ratio [ M:L] was [l:l] for Ag(I)and Au(III) ions but [l:2] for Pt(IV) ion. The metal complexes of Au(III) and pt (IV) was l:l and l:2 electrolyte receptivity while the Ag(I) complex is non electrolyte . In this study the cytoxicity of Ag(I), Au(III), and Pt (IV) complexes on humn (PC3) breast cancer and normal cells were MTT assay .
Keywords
Azo; schiff base; metal complexes and anticancer (breast cancer)
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