ANTIBACTERIAL EFFICACY OF A MOUTHWASH CONTAINING HYDROXYAPATITE NANOPARTICLES ALONE OR IN COMBINATION WITH CHLORHEXIDINE/FLUORIDE | ||||
Egyptian Dental Journal | ||||
Article 32, Volume 62, Issue 1 - January (Part 2), January 2016, Page 577-581 PDF (241.61 K) | ||||
DOI: 10.21608/edj.2016.92744 | ||||
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Authors | ||||
Omnia Magdy Mostafa1; Enas Hussein Mobarak2; Heba Ahmed El-Deeb3; Mohamed Riad Farid2 | ||||
1B. D. Sc. (Cairo University, 2008) | ||||
2Professor, Operative Dentistry Department , Faculty of Oral and Dental Medicine, Cairo University | ||||
3Associate Professor, Operative Dentistry Department, Faculty of Oral and Dental Medicine, Cairo University | ||||
Abstract | ||||
Aim: This study was carried out to evaluate the antibacterial activity of a mouthwash containing clusters of zinc-carbonate hydroxyapatite nanoparticles in combination with chlohexidine or fluoride. Materials and methods: Antimicrobial agents used in this study were Chlorhexidine diacetate, Sodium fluoride powder and Dr.Wolff’s Biorepair against Streptococcus mutans (MS). In this study, the relative antimicrobial efficacy of newly introduced zinc-carbonate hydroxyapatite nanoparticels containing mouthwash, chlorhexidine, sodium fluoride and their combination against MS was tested. The MS was inoculated onto its specified culturel media. Agar diffusion test is done. The inhibition zone diameters were measured. Mean inhibition zone diameters were recorded and statistically analyzed Result: For the effect of the tested antibacterial on the Streptococcus mutans, results showed that the mean diameter and standard deviation of inhibition zone (mm) for chlorhexidine (CHX) was 23.9 (2.04) mm, sodium fluoride (NaF) was 12.2 (0.75) mm, hydroxyapatite microclusters containing mouthwash (HAPMC) was 18.2 (1.3) mm, HAPMC+CHX was 22.5 (2.6) mm and HAPMC+NaF was 18.7 (1.8) mm. Conclusion: Hydroxyapatite microclusters containing mouthwash had a potential antimicrobial activity against MS alone or in combination with other antimicrobials | ||||
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