SEROPREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG FAMILY MEMBERS OF INFECTED AND NON-INFECTED SYMPTOMATIC CHILDREN
HAMED, M., HUSSEIN, H., EL SADANY, H., ELGOBASHY, A., ATTA, A. (2013). SEROPREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG FAMILY MEMBERS OF INFECTED AND NON-INFECTED SYMPTOMATIC CHILDREN. EKB Journal Management System, 43(3), 755-766. doi: 10.21608/jesp.2013.93322
MOHAMMED E. HAMED; HATEM M. HUSSEIN; HOSAM F. EL SADANY; ASHGAN A. ELGOBASHY; AMAL H. ATTA. "SEROPREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG FAMILY MEMBERS OF INFECTED AND NON-INFECTED SYMPTOMATIC CHILDREN". EKB Journal Management System, 43, 3, 2013, 755-766. doi: 10.21608/jesp.2013.93322
HAMED, M., HUSSEIN, H., EL SADANY, H., ELGOBASHY, A., ATTA, A. (2013). 'SEROPREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG FAMILY MEMBERS OF INFECTED AND NON-INFECTED SYMPTOMATIC CHILDREN', EKB Journal Management System, 43(3), pp. 755-766. doi: 10.21608/jesp.2013.93322
HAMED, M., HUSSEIN, H., EL SADANY, H., ELGOBASHY, A., ATTA, A. SEROPREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG FAMILY MEMBERS OF INFECTED AND NON-INFECTED SYMPTOMATIC CHILDREN. EKB Journal Management System, 2013; 43(3): 755-766. doi: 10.21608/jesp.2013.93322

SEROPREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG FAMILY MEMBERS OF INFECTED AND NON-INFECTED SYMPTOMATIC CHILDREN

Journal of the Egyptian Society of Parasitology
Article 20, Volume 43, Issue 3, December 2013, Page 755-766  XML PDF (280.22 K)
Document Type: Original Article
DOI: 10.21608/jesp.2013.93322
View on SCiNiTO View on SCiNiTO
Authors
MOHAMMED E. HAMED1; HATEM M. HUSSEIN1; HOSAM F. EL SADANY1; ASHGAN A. ELGOBASHY1; AMAL H. ATTA2
1Department of Pediatrics, Faculty of Medicine, Zagazig University, Egypt.
2Department of Microbiology, Faculty of Medicine, Zagazig University, Egypt.
Abstract
This study determined the prevalence of seropositivity of anti-H. pylori IgG antibodies, and evaluated some socio-epidemiologic characteristics among family members of infected and non-infected symptomatic children. One hundred children with upper gastrointestinal symptoms without previous H. pylori eradication treatment were prospectively studied by both upper endoscopy with histopathological biopsies examination, and serum anti-H. pylori IgG test between July 2012 to June 2013. The patients were subdivided into: H. pylori infected children (GӀ), and H. pylori non-infected children (GӀӀ). Also, 320 of their family members were examined for serum anti-H. pylori IgG and stool antigen tests. Sheets were filled out included personal and medical history. The results showed statistically significant difference between both groups as regard dyspepsia, anemia, and histopathological findings (chronic active gastritis, peptic ulcer, and duodenitis). Family members were subdivided into: those of H.pylori infected symptomatic children (165) and those of H. pylori non-infected
symptomatic children (155). Anti-H. pylori IgG prevalence was significantly higher in relatives of GI than those of GII (69.1% vs. 29%; p<0.05). The seroprevalence of H.pylori infection in all family members was (49.7%). Mothers of GI showed the highest seroprevalence (39.5%) as compared to fathers and siblings (22.8%, & 37.7%, respectively). Relatives of GI with low socioeconomic status, and lived in rural area showed the highest seroprevalence (82.5%, &78.1 % respectively)
Keywords
Helicobacter pylori; IgG-positivity; Children; Parents; Socioepidemiology
Statistics
Article View: 94
PDF Download: 148