DIAGNOSTIC USEFULNESS OF THE RANDOM URINE NA/K RATIO IN PREDICTING THERAPEUTIC RESPONSE FOR DIURETICS IN CIRRHOTIC PATIENTS WITH ASCITES
MOHII, E., EL MANSY, I., SALAH, M., KHEDR, M. (2013). DIAGNOSTIC USEFULNESS OF THE RANDOM URINE NA/K RATIO IN PREDICTING THERAPEUTIC RESPONSE FOR DIURETICS IN CIRRHOTIC PATIENTS WITH ASCITES. EKB Journal Management System, 43(3), 767-776. doi: 10.21608/jesp.2013.93323
EL SAYED M. MOHII; ISMAIL M. EL MANSY; MOHAMED SALAH; MOHAMED ABD ELHAMID KHEDR. "DIAGNOSTIC USEFULNESS OF THE RANDOM URINE NA/K RATIO IN PREDICTING THERAPEUTIC RESPONSE FOR DIURETICS IN CIRRHOTIC PATIENTS WITH ASCITES". EKB Journal Management System, 43, 3, 2013, 767-776. doi: 10.21608/jesp.2013.93323
MOHII, E., EL MANSY, I., SALAH, M., KHEDR, M. (2013). 'DIAGNOSTIC USEFULNESS OF THE RANDOM URINE NA/K RATIO IN PREDICTING THERAPEUTIC RESPONSE FOR DIURETICS IN CIRRHOTIC PATIENTS WITH ASCITES', EKB Journal Management System, 43(3), pp. 767-776. doi: 10.21608/jesp.2013.93323
MOHII, E., EL MANSY, I., SALAH, M., KHEDR, M. DIAGNOSTIC USEFULNESS OF THE RANDOM URINE NA/K RATIO IN PREDICTING THERAPEUTIC RESPONSE FOR DIURETICS IN CIRRHOTIC PATIENTS WITH ASCITES. EKB Journal Management System, 2013; 43(3): 767-776. doi: 10.21608/jesp.2013.93323

DIAGNOSTIC USEFULNESS OF THE RANDOM URINE NA/K RATIO IN PREDICTING THERAPEUTIC RESPONSE FOR DIURETICS IN CIRRHOTIC PATIENTS WITH ASCITES

Journal of the Egyptian Society of Parasitology
Article 21, Volume 43, Issue 3, December 2013, Page 767-776  XML PDF (257.38 K)
Document Type: Original Article
DOI: 10.21608/jesp.2013.93323
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Authors
EL SAYED M. MOHII1; ISMAIL M. EL MANSY2; MOHAMED SALAH2; MOHAMED ABD ELHAMID KHEDR3
1Department of Tropical Medicine, Faculty of Medicine, Al-Azhar University, Nasr City, Egypt.
2Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Nasr City, Egypt.
3Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Nasr City, Egypt.
Abstract
Ascites is a major complication of liver cirrhosis which carries a poor prognosis. Diuretics are used in treatment of ascites in addition to salt restriction. Monitoring of diuretic response can be achieved by measurement of 24 hours urinary sodium. This study evaluated the accuracy of using spot urinary sodium/potassium ratio as a reliable alternative to 24 hours urinary sodium in assessment of dietary sodium compliance in patients with liver cirrhosis receiving diuretics.
Fifty patients presented with liver cirrhosis and ascites were divided into 2 groups: GI 14 (28%) patients diuretic resistant with 24 hours urinary sodium < 78 mEq) and GII 36 (72%) patients diuretic sensitive with 24 hours urinary sodium >
78 mEq. The results showed highly significant correlation between 24 hours urinary sodium and spot urine sodium/potassium ratio with sensitivity 87.5% specificity 56% and accuracy 70% at cutoff point of 1.8.
Keywords
Cirrhotic patients; Ascites; Therapeutic response; Urine Na/K Ratio
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