CONSUMPTION HAZARDS OF CATTLE LIVER INFECTED WITH FASCIOLA SPP.: II. EXPERIMENTAL STUDY ON RATS | ||||
| Journal of the Egyptian Society of Parasitology | ||||
| Article 24, Volume 43, Issue 3, December 2013, Page 797-804 PDF (300.88 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jesp.2013.93326 | ||||
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| Authors | ||||
| FAROUK M. EL-TELLAWY1; REFAAT M. KHALIFA2; MONA K. ABD EL-KADER3; AMANY O. MOHAMED4; NOHA S. AHMED5 | ||||
| 1Nutrition Technology, Institute of Environmental Studies and Researches, Egypt. | ||||
| 2Department of Parasitology, Faculty of Medicine, Assiut University, Egypt. | ||||
| 3Department of Nutrition, Faculty of Home Economics, Helwan University, Egypt. | ||||
| 4Department of Biochemistry, Faculty of Medicine, Assiut University, Egypt. | ||||
| 5Department of Home Economics,Faculty of Specific Education, Al- Fayoum University, Egypt. | ||||
| Abstract | ||||
| This study evaluated and revealed the consumption hazards of cattle liver infected with Fasciola spp. and revealed its effects on the serum estimation of liver enzyme (ALT) on experimental rats. A total of 42 Wister albino rats were classified into 7 groups. Four groups were fed on raw and cooked cattle liver with various intensity of Fasciola spp. infection. Two groups were fed on raw and cooked normal cattle liver (positive control), and one group served as negative control. Histopathology of the rats' liver revealed hydropic degeneration, congestion with dilatation of the central vein and sinusoids and focal areas of necrosis. The intestine samples showed degenerative changes and necrobiosis of the villar epithelium with inflammatory cell infiltration. Moreover, a slight increase was noticed in the liver enzyme ALT which is known to be an important marker of liver destruction. | ||||
| Keywords | ||||
| Fasciola spp; rats; Histopathology; liver; intestine; ALT | ||||
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