Rheumatoid Arthritis, Pathophysiology and Management | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 5, Volume 70, Issue 11, January 2018, Page 1898-1903 PDF (242.34 K) | ||||
Document Type: Original Article | ||||
View on SCiNiTO | ||||
Authors | ||||
Ghofran Noor Mohammad Qorban1; Mohannad Mobarak Omar Badghaish 2; Abdulmohsen Shawan Albaqami3; Ameera Ahmad Nemer4; Aisha Jamal Alali5; Rawan Fouad Hassan Al Yaqoub6; Homoud Abdulaziz Alshamrani7; Omar Hasan Badahman2; Rahma Abdulkarim Ansaif8; Metab Ali Alasmari9; Arwa Yahya Alghamdi4; Hussain Ahmad Saud Alshareef10; Alanoud Mohammed Aljadeed6; Ayman Ahmed Almohammed11; Doaa Mohammad Filmban12; Abdulrahman Saleh Alaql13 | ||||
1King Abdulaziz University Hospital | ||||
2King Abdulaziz University | ||||
3Imam Muhammad Ibn Saud Islamic University | ||||
4Immam Abdulrahman Faisal University | ||||
5Arabian Gulf University | ||||
6Ibn Sina National College | ||||
7Primary Health Care Center – Riyadh | ||||
8Alexandria University | ||||
9Gizan Militarily Hospital | ||||
10King Fahad Hospital, Madinah | ||||
11King Faisal University | ||||
12Al Noor Specialist Hospital | ||||
13Al Adeel Primary Health Care Center | ||||
Abstract | ||||
Introduction: Rheumatoid arthritis is considered one of the most common, and particularly attacks the joint causing significant individual and community burden, and present with articular as well as extra articular manifestation. Treatment modalities of rheumatoid arthritis have dramatically improved in recent years, significantly decreasing long-term auricular and extra-auricular complications. Aim of the work: this review was aimedto study the pathophysiology, clinical picture, and management of rheumatoid arthritis, with focus on the newer modalities. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: rheumatoid arthritis, chronic inflammatory disorders, genetic of rheumatoid arthritis, management of rheumatoid arthritis, DMARD, biological agents Conclusion: The newer modality of treatment must include disease-modifying antirheumatic drug (DMARDs) which must be started as early as possible. Combining DMARDs with corticosteroids will result in significantly better outcomes than monotherapy with any DMARD and decrease long term morbidity associated with this condition. | ||||
Keywords | ||||
chronic inflammatory disorders; management of rheumatoid arthritis; DMARD; Biological agents; Rheumatoid Arthritis | ||||
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