Crohn’s Disease: Pathophysiology, and Management | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 24, Volume 70, Issue 11, January 2018, Page 2004-2007 PDF (248.12 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejhm.2018.9407 | ||||
View on SCiNiTO | ||||
Authors | ||||
Dima Ammar Fatahi 1; Abdullah Saad Al Asmari2; Ghadah Abdulrahman Bukhari3; Homoud Abdulaziz Alshamrani4; Khalid Abdullah Hunaydi5; Ahmad Mufarreh Sharahili5; Tahani Khalid Alharshan6; Anhar Ali Alherz7 | ||||
1Tishreen University | ||||
2Taif University | ||||
3Ibn Sina National College | ||||
4Primary Health Care Center, Riyadh | ||||
5Aseer Central Hospital | ||||
6King Faisal University | ||||
7King Faisal General Hospital | ||||
Abstract | ||||
Background: The incidence of crohn’s disease reaches up to 20 per 100,000 people per year, with a median age of 30 years, and is higher in the developed world. Although the exact cause and pathophysiology is unknown, several environmental and genetic factors have been linked with higher risk or severity of the disease. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: crohn’s disease, inflammatory bowel disease, genetics of crohn’s disease, diagnosis of IBD, management crohn’s disease Aim of the study: In this review, we aim to study the pathophysiology, diagnosis and management of crohn’s disease. We will pay special attention to the newer biological drugs used in management. Conclusion: Crohn’s disease is usually managed with medical treatment, although many patients will need to undergo surgery at least once. Treatment usually aims at the induction and maintenance of a remission without the excessive use and dependence of steroids. Achieving higher quality of life is the main goal of any modality of treatment. | ||||
Keywords | ||||
Crohn’s disease; inflammatory bowel disease; medical management for crohn’s disease | ||||
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