Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)
Hamed, A., Beshr, A., Behairy, R., Eladawy, I. (2020). Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS). EKB Journal Management System, 2(3), 547-553. doi: 10.21608/ijma.2020.27101.1119
Alaa Ameen Hamed; Amal Elsebaie Beshr; Reda Mohamed Behairy; Iman Ibrahim Eladawy. "Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)". EKB Journal Management System, 2, 3, 2020, 547-553. doi: 10.21608/ijma.2020.27101.1119
Hamed, A., Beshr, A., Behairy, R., Eladawy, I. (2020). 'Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)', EKB Journal Management System, 2(3), pp. 547-553. doi: 10.21608/ijma.2020.27101.1119
Hamed, A., Beshr, A., Behairy, R., Eladawy, I. Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS). EKB Journal Management System, 2020; 2(3): 547-553. doi: 10.21608/ijma.2020.27101.1119

Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)

International Journal of Medical Arts
Article 9, Volume 2, Issue 3, July 2020, Page 547-553  XML PDF (377.2 K)
Document Type: Original Article
DOI: 10.21608/ijma.2020.27101.1119
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Authors
Alaa Ameen Hamed1; Amal Elsebaie Beshr2; Reda Mohamed Behairy2; Iman Ibrahim Eladawy email orcid 2
1Resident at Department of Otorhinolaryngology [Audiovestibular Unit], Faculty of Medicine for Girls, Al-Azhar University, Egypt
2Department of Otorhinolaryngology, Faculty of Medicine for Girls [Cairo], Al-Azhar University, Egypt
Abstract
Background: Involvement of the brainstem in multiple sclerosis [MS] has significant implications on the disease course and can be presented with different symptoms. There are many tests able to detect brain-stem involvement in MS with various degrees of success.
Aim of the work: To study the changes in vestibular evoked myogenic potential [VEMP], in patients with MS, and to detect its sensitivity for detection of the brain-stem lesions previously diagnosed with magnetic resonance imaging [MRI] in MS patients.
Patients and Methods: Sixty participants had been enrolled and divided into two groups: 30 healthy subjects [Control group] and 30 MS patients [Study group]. Both groups had been subjected to otological examinations, pure tone audiometry, acoustic impedance, cervical vestibular evoked myogenic potential [cVEMP], ocular vestibular evoked myogenic potential [oVEMP] and MRI. 
Results: In MS group, oVEMP mean latencies of n1 and p1 and cVEMP mean p13 and n23 latencies were significantly prolonged. In addition, 14 MS patients [46.7%] had brainstem lesions as confirmed by MRI. Finally, oVEMP test had higher sensitivity than the cVEMP in prediction of brainstem lesions.
Conclusion: oVEMP seems to be useful and more sensitive than cVEMP as an adjunct test in the evaluation of brain-stem dysfunction in MS patients. 
Keywords
Multiple Sclerosis [MS]; Vestibular Evoked Myogenic Potential [VEMP]; Cervical; Vestibular function; Ocular
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