Infantile Central Myofibroma of the Mandible: | ||||
| Egyptian Journal of Oral and Maxillofacial Surgery | ||||
| Article 2, Volume 10, Issue 2, April 2019, Page 58-63 PDF (1.03 MB) | ||||
| Document Type: Case Report | ||||
| DOI: 10.21608/omx.2019.19202.1042 | ||||
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| Authors | ||||
| Ibrahim Nowair1; Mohamed Eid* 1; Basant AbouZaid2; Heba Youssef2 | ||||
| 1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University, Tanta, Egypt | ||||
| 2Department of Oral Pathology, Faculty of Dentistry, Tanta University, Tanta, Egypt | ||||
| Abstract | ||||
| Oral myofibroma is an uncommon benign tumor that has great tendency to involve oral soft tissues with bony involvement remains a rarity. Most myofibromas exhibit a benign slow clinical course however intra-osseous lesions could be mistaken with many aggressive tumors which necessitate accurate diagnosis. The aim of this report is to shed light on a rare case of infantile central myofibroma of the mandible. Case report: A 6-month-old girl presented with an expansible painless left mandibular swelling. Radiographic examination revealed a well-defined, unilocular, radiolucent lesion with cortical erosions. Histopathological examination showed a highly cellular, encapsulated mass comprised of spindle-shaped and smaller round or polygonal cells in a vague biphasic pattern. Immunohistochemically, tumor cells showed strong cytoplasmic staining for α-SMA, weak Ki-67 and negative desmin, CD34 and S-100 protein. Accordingly, conservative surgical excision with bone curettage was performed. Postoperative follow-up revealed excellent healing with no evidence of recurrence. | ||||
| Keywords | ||||
| Intra-osseous; mandible; myofibroblast; oral myofibroma; α-SMA | ||||
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