Infantile Central Myofibroma of the Mandible: | ||||
Egyptian Journal of Oral and Maxillofacial Surgery | ||||
Article 2, Volume 10, Issue 2, April 2019, Page 58-63 PDF (1.03 MB) | ||||
Document Type: Case Report | ||||
DOI: 10.21608/omx.2019.19202.1042 | ||||
View on SCiNiTO | ||||
Authors | ||||
Ibrahim Nowair1; Mohamed Eid* 1; Basant AbouZaid2; Heba Youssef2 | ||||
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University, Tanta, Egypt | ||||
2Department of Oral Pathology, Faculty of Dentistry, Tanta University, Tanta, Egypt | ||||
Abstract | ||||
Oral myofibroma is an uncommon benign tumor that has great tendency to involve oral soft tissues with bony involvement remains a rarity. Most myofibromas exhibit a benign slow clinical course however intra-osseous lesions could be mistaken with many aggressive tumors which necessitate accurate diagnosis. The aim of this report is to shed light on a rare case of infantile central myofibroma of the mandible. Case report: A 6-month-old girl presented with an expansible painless left mandibular swelling. Radiographic examination revealed a well-defined, unilocular, radiolucent lesion with cortical erosions. Histopathological examination showed a highly cellular, encapsulated mass comprised of spindle-shaped and smaller round or polygonal cells in a vague biphasic pattern. Immunohistochemically, tumor cells showed strong cytoplasmic staining for α-SMA, weak Ki-67 and negative desmin, CD34 and S-100 protein. Accordingly, conservative surgical excision with bone curettage was performed. Postoperative follow-up revealed excellent healing with no evidence of recurrence. | ||||
Keywords | ||||
Intra-osseous; mandible; myofibroblast; oral myofibroma; α-SMA | ||||
Statistics Article View: 148 PDF Download: 256 |
||||