IMPACT OF HEPATOCELLULAR CARCINOMA ON HEALTH RELATED QUALITY OF LIFE IN EGYPTIAN PATIENTS: A SINGLE CENTRE STUDY | ||||
| Journal of the Egyptian Society of Parasitology | ||||
| Article 15, Volume 43, Issue 1, April 2013, Page 183-194 PDF (301.77 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jesp.2013.94859 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| HASSAN HAMDY; EMAN MAHMOUD FATHY BARAKAT; RUNIA FOUAD EL FOLLY | ||||
| Department of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt. | ||||
| Abstract | ||||
| Among patients with chronic liver disease, impairment in HRQOL has been reported. Hepatocellular carcinoma (HCC) is one of the major squeal of chronic liver diseases. So, relationship between subjective HRQOL and HCC must be analysed. This study assessed the effect of HCC on HRQOL, and its loco-regional treatment on HRQOL. Forty patients with HCV related chronic liver disease as a control group was enrolled in the study. Eighty HCC patients on top of chronic HCV liver disease categorized according to the modality of loco-regional treatment (BCLC staging system) into GI; 40 HCC patients treated with radiofrequency ablation (RFA) and GII; 40 HCC patients treated with trans-arterial chemoembolization (TACE). The SF-36 questionnaire was performed before and one month after the intervention. Comparing the parameters of HRQOL in GI before and after RFA, and in GII before and after TACE; there was a statistically significant improvement in group I. However, the improvement in group II (TACE) was non-significant (P>0.05). | ||||
| Keywords | ||||
| Hepatocellular carcinoma; Heath Related Quality of Life; Barcelona- Clinic Liver Cancer; Radiofrequency; Trans-arterial chemoembolization | ||||
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