The relation between vitamin D level in the third trimester and preeclampsia
alsaeed, S., Mohammed, N., Nassef, A., Almadbouly, A. (2020). The relation between vitamin D level in the third trimester and preeclampsia. EKB Journal Management System, 10(2), 127-132. doi: 10.21608/ebwhj.2019.21449.1068
shaema alsaeed; Nahed H. Mohammed; Aziza H. Nassef; Asmaa Abd Elsalam Almadbouly. "The relation between vitamin D level in the third trimester and preeclampsia". EKB Journal Management System, 10, 2, 2020, 127-132. doi: 10.21608/ebwhj.2019.21449.1068
alsaeed, S., Mohammed, N., Nassef, A., Almadbouly, A. (2020). 'The relation between vitamin D level in the third trimester and preeclampsia', EKB Journal Management System, 10(2), pp. 127-132. doi: 10.21608/ebwhj.2019.21449.1068
alsaeed, S., Mohammed, N., Nassef, A., Almadbouly, A. The relation between vitamin D level in the third trimester and preeclampsia. EKB Journal Management System, 2020; 10(2): 127-132. doi: 10.21608/ebwhj.2019.21449.1068

The relation between vitamin D level in the third trimester and preeclampsia

Evidence Based Women's Health Journal
Article 2, Volume 10, Issue 2, May 2020, Page 127-132  XML PDF (563.84 K)
Document Type: Original Article
DOI: 10.21608/ebwhj.2019.21449.1068
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Authors
shaema alsaeed1; Nahed H. Mohammed2; Aziza H. Nassef2; Asmaa Abd Elsalam Almadbouly3
1Obstetrics and Gynecology Department, Dar Elsalam General Hospital
2Faculty of Medicine for Girls, Al-Azhar University
3Department of Clinical Pathology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
Abstract
Introduction: Preeclampsia (PE) affects 2%–8% of all pregnancies and remains a leading cause of maternal and perinatal mortality and morbidity. Vitamin D was considered important for bone and calcium. There is some evidence now that low levels of Vitamin D are associated with the risk of preeclampsia but more studies are needed to prove the same.
Aim of the work: The aim of our study was to assess the relation between the vitamin D deficiency and the occurrence of preeclampsia in the third trimester of pregnancy.
Patients and Methods: This is a prospective case control study, where 90 pregnant women between 27-40 weeks of gestation were recruited from the outpatient clinic in Al zahraa university hospital, they subjected to 25(OH) vit D level estimations and transabdominal ultrasound. Follow up was done till delivery to assess occurrences of preeclampsia and assessment of fetal outcome. Cases were divided into control (n=30) and preeclampsia (n=60) groups. According to the severity, the preeclampsia cases were subdivided to mild (n=40) and severe preeclampsia(n=20)..
Results: The two groups (PE and Control ) were comparable regarding maternal age, BMI and gestational age. There was significant relation between deficient 25-(OH) vitamin D and BMI. Patients with severe preeclampsia had significant lower level of 25-OH D than the mild preeclampsia and normotensive patients. There was no significant difference in 25(OH)vit D level between mild preeclampsia and control group.
Conclusion: there were significant association between vitamin D deficiency and severe preeclampsia. Vitamin D deficiency may be a risk factor for preeclampsia and may be helpful for prediction of preeclampsia and its severity.
Keywords
Deficient 25-OH vit D; 25(OH) vitamin D; preeclampsia
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