Effect of oxytocin infusion on reducing the blood loss during abdominal myomectomy: A randomized double-Blind controlled trial | ||||
Evidence Based Women's Health Journal | ||||
Article 4, Volume 10, Issue 2, May 2020, Page 144-149 PDF (922.81 K) | ||||
Document Type: Original Article | ||||
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Authors | ||||
Mohammad Abd El-Hameed Mohammad Nasr Al-Deen1; Ahmed Nageeb1; Mohamed Elsenity 2; Othman Mohammed1; Othman Mohammed Abbas3 | ||||
1Department of Obstetrics and Gynecology, Faculty of Medicine, Ain-Shams University | ||||
2Department of Obstetrics & Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||||
3Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Egypt | ||||
Abstract | ||||
Background: Oxytocin is the agent of choice in the prevention of postpartum uterine atony and bleeding. This study aims at assessment of the efficacy of oxytocin infusion on reducing blood loss during abdominal myomectomy.Materials and Methods: The current study was a randomized double-blind controlled trial conducted in a tertiary University Hospital. The study participants were randomized to one of two groups; Group 1 included 30 women received 30 IU of (Oxytocin) in 500 ml normal saline administered during abdominal myomectomy and Group 2 included 30 women received only saline infusion administered during the surgery. The primary outcome is the difference in mean blood loss in both groups.Results: The estimated blood loss was significantly lower among oxytocin group in comparison to the control group as well as significantly higher Postoperative hemoglobin and hematocrit with significantly lower Hematocrit reduction (p<0.001). It showed also significant less blood transfusion in the post operative period among oxytocin group (p=0.044) as well as significantly shorter operative duration, ambulation time and duration of hospital stay.Conclusion:Oxytocin infusion could reduce the blood loss during abdominal myomectomy in the lowest effective and safest dose. | ||||
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