Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study
Ali, M., Abdel Rahman, R., Wahba, N., Gaber, M. (2020). Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study. EKB Journal Management System, 10(2), 176-180. doi: 10.21608/ebwhj.2020.28672.1095
Mohamed Sayed Ali; Rehab Mohamed Abdel Rahman; Nancy Samir Wahba; Mohamed Gaber. "Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study". EKB Journal Management System, 10, 2, 2020, 176-180. doi: 10.21608/ebwhj.2020.28672.1095
Ali, M., Abdel Rahman, R., Wahba, N., Gaber, M. (2020). 'Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study', EKB Journal Management System, 10(2), pp. 176-180. doi: 10.21608/ebwhj.2020.28672.1095
Ali, M., Abdel Rahman, R., Wahba, N., Gaber, M. Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study. EKB Journal Management System, 2020; 10(2): 176-180. doi: 10.21608/ebwhj.2020.28672.1095

Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study

Evidence Based Women's Health Journal
Article 8, Volume 10, Issue 2, May 2020, Page 176-180  XML PDF (957.69 K)
Document Type: Case Report
DOI: 10.21608/ebwhj.2020.28672.1095
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Authors
Mohamed Sayed Ali1; Rehab Mohamed Abdel Rahman2; Nancy Samir Wahba3; Mohamed Gaber email 4
1Department of Obstetrics and Gynecology, Ain-Shams University, Cairo
2Department of Obstetrics and Gynecology, Faculty of Medicine, Ain-Shams University.
3Department of Clinical Pathology, Faculty of Medicine, Ain-Shams University, Cairo
4Obstetrics and Gynecology Department, Faculty of Medicine, Kafr Elsheikh University
Abstract
Background: Thyroid dysfunction and autoimmunity are relatively common clinical scenario in women within reproductive age group and have been correlated and linked to a spectrum of adverse pregnancy outcomes such as recurrent miscarriage.  Aim: To investigate the correlation and linkage between anti-TPO antibody and recurrent miscarriage.
Materials and Methods: This case control observational research study was conducted on 90 pregnant female out which 45 with history of recurrent miscarriage were cases and 45 without such history were controls.
Results: The mean age of control group was 25.29 while it was 26.69 in cases group. The prevalence of anti-tpo antibody positivity in the study group was 18.8%.out of 90 pregnant female ;17 were positive for anti-tpo antibody. The prevalence of thyroid autoimmunity in pregnant women with recurrent abortion was (37.8%) while it was (0%) in the healthy group (P=0.0).  Conclusion:There was significant relationship between anti thyroid antibody positivity and recurrent miscarriage. Thyroid autoimmunity can be considered as risk marker for recurrent miscarriage.
Keywords
Anti-tpo antibody; pregnancy; recurrent miscarriage
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