Antibacterial activity of cupric oxide nanoparticles against pathogenic bacteria | ||
| Journal of Basic and Environmental Sciences | ||
| Volume 4, Issue 1, January 2017, Pages 90-93 PDF (56.33 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jbes.2017.369634 | ||
| Authors | ||
| Ahmed M. Azzama1; Mahmoud M. Hazaab2; Ashraf M. El Saeed3; Marwa R. Hamed4 | ||
| 1Environmental Researches Department, Theoder Bilharz Research Institute, Egypt | ||
| 2a Environmental Researches Department, Theoder Bilharz Research Institute, Egypt | ||
| 3Petroleum Application Department, Egyptian Petroleum Research Institute, Egypt. | ||
| 4Microbiology Department, Faculty of Science, Banha University, Egypt. | ||
| Abstract | ||
| Nano materials have a wide range of applications due to their interesting size-dependent chemical and physical properties compared to particles of size in the range of micrometer. In this study, we studied the structural and antimicrobial properties of cupric oxide nanoparticles (CuO NPs) that synthesized by the sol–gel method and characterized by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The antimicrobial activity of CuO NPs was evaluated against gram-negative bacteria (Escherichia coli) and gram-positive bacteria (Staphylococcus aureus) using agar-well diffusion method and minimum inhibition concentration (MIC). The average diameter of synthesized CuO NPs was 25.8 nm with approximately round-shape particles. CuO NPs showed excellent antimicrobial activity against both E. coli and S. aureus, but gram-positive bacteria is more sensitive to CuO NPs than gram-negative one, where the MIC of S. aureus and E. coli were 15 and 22 µg/ml, respectively. So, CuO NPs could be suggested as new effective agents of multidrug-resistant bacteria. | ||
| Keywords | ||
| Cupric oxide; Nanoparticles; Antibacterial activity; Bacteria | ||
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