Synthesis and characterization of diquaternary di-Schiff base compounds and their potential as antimicrobial agents against different types of microorganisms | ||
| Journal of Basic and Environmental Sciences | ||
| Volume 7, Issue 1, January 2020, Pages 13-21 PDF (575.9 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jbes.2020.371133 | ||
| Authors | ||
| Ahmed H. Moustafa* 1; Galal H. Sayed2; Kh. Zakaria3; Nabel A. Negm3 | ||
| 1Khalda Petroleum Company, Cairo, EGYPT. | ||
| 2Chemistry department, Faculty of Science, Ain Shams University, Cairo, EGYPT. | ||
| 3Egyptian Petroleum Research Institute, Cairo, EGYPT. | ||
| Abstract | ||
| Three Schiff base compounds were prepared from the reaction of acetophenone and o-phenylene diamine, p-phenylene diamine and benzoimidazole designated as (AH1-AH3). The products were reacted by dimethyl sulfate to obtain three diSchiff base cationic derivatives (AH4-6). The chemical structures of the prepared diSchiff bases and their cationic derivatives were confirmed using elemental analysis, infrared spectroscopy and nuclear magnetic resonance spectra. The prepared cationic derivatives were evaluated for their antimicrobial activities against Gram-positive, Gram-negative and sulfate reducing bacteria. The evaluation was involved inhibition zone diameter and minimum inhibitory concentration measurements. The results showed that the chemical structures of the compounds play an effective role on their antimicrobial efficiency. | ||
| Keywords | ||
| Schiff base; cationic biocides; inhibition zone diameter; minimum inhibition concentration | ||
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