Toxoplasmosis: Status, control strategies and prospective challenges | ||
| Parasitologists United Journal | ||
| Article 7, Volume 18, Issue 2, September 2025, Pages 133-143 PDF (405.56 K) | ||
| Document Type: Review Article | ||
| DOI: 10.21608/puj.2025.393988.1301 | ||
| Authors | ||
| Khloud K Mohsen* ; Marwa A. Gouda; Ayman A Abdel-Wahab | ||
| Department of Clinical and Molecular Parasitology, National Liver Institute, Menoufia University, Menoufia, Egypt | ||
| Abstract | ||
| Toxoplasmosis is a widespread disease infecting about one-third of the world’s human population. Until now, a live-attenuated vaccine (Toxovax) is the only commercially available vaccine that has several limitations for use in humans, while the current treatment for toxoplasmosis has limited efficacy in eradicating the infection and is associated with several side effects. Therefore, the search for effective preventive and control strategies for toxoplasmosis is mandatory. This comprehensive review aims to provide the current and emerging strategies for control of toxoplasmosis. The study highlights different approaches to control toxoplasmosis that include public health education regarding the hazards of the parasite and precautions that should be taken to avoid infection; procedures generally done to ensure sanitary food and water supplies; preventive screening measures to prevent transmission of toxoplasmosis through organ transplantation and blood donation; advanced diagnostic techniques; emerging chemotherapeutic targets, and promising vaccines for toxoplasmosis. | ||
| Keywords | ||
| chemotherapy; control measures; diagnostic tools; drug targets; nanotechnology; toxoplasmosis; vaccination | ||
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