Association Between Fluid Balance and Outcome Variables in Mechanically Ventilated Children. | ||
| Benha Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 01 November 2025 PDF (594.79 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.364837.2337 | ||
| Authors | ||
| Eman G. Abdel Rahman1; Reda S. Afifi2; Ahlam E. Baraka* 3; Marwa E. Ahmed1 | ||
| 1Lecturer of Pediatrics Faculty of Medicine - Benha University | ||
| 2Professor of Pediatrics Faculty of Medicine - Benha University | ||
| 3M.B.B.Ch Faculty of Medicine – Tanta University | ||
| Abstract | ||
| Background: Intravenous (IV) fluid therapy is often required in patients undergoing mechanical ventilation (MV) to restore hemodynamics and distal organ perfusion.. Prolonged mechanical ventilation (PMV) in critically ill children is associated with significant complications, including fluid balance disturbances. Understanding the relationship between fluid balance and PMV can improve patient outcomes. This study aimed to evaluate the association between fluid balance and PMV in critically ill children, as well as other outcomes like pediatric mortality index (PIM2),length of PICU stay & outcome of the patients . Methods: This cross sectional study was conducted on 40 mechanically ventilated children admitted to the pediatric intensive care unit (PICU) at Benha University Hospital from January to June 2023. Fluid balance was calculated during the first 48 hours of mechanical ventilation. PIM2 scores and other clinical parameters were recorded. Results: The mean age of patients was 4.1 ± 4.57 years. A significant positive correlation was found between fluid balance in the first 48 hours and PIM2 (r=0.568, P<0.001), as well as with the length of PICU stay (r=0.757, P<0.001). Fluid balance was significantly higher in non-survivors compared to survivors (P=0.003). Logistic regression identified high-risk diagnosis, diastolic blood pressure, fluid balance, PIM2, and duration of MV as significant predictors of mortality. Conclusion: Positive fluid balance in the first 48 hours is significantly associated with PMV and higher mortality in critically ill children. Early fluid management may improve outcomes in this population. | ||
| Keywords | ||
| Fluid Balance; Prolonged Mechanical Ventilation, PICU, PIM2, Mortality | ||
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