Effect of Mesenchymal Stem Cell Injection on Healing Outcome in Secondary Cleft Lip Correction
Zakeer, S., Al.Ahmady, H., Adly, N., Zidan, A., Abd Alzeem, A. (2020). Effect of Mesenchymal Stem Cell Injection on Healing Outcome in Secondary Cleft Lip Correction. EKB Journal Management System, 7(4-B), 599-605. doi: 10.21608/adjg.2020.23227.1229
Somaya M. Zakeer; Hatem H. Al.Ahmady; Nahed M. Adly; Ahmed M. Zidan; ahmed F. Abd Alzeem. "Effect of Mesenchymal Stem Cell Injection on Healing Outcome in Secondary Cleft Lip Correction". EKB Journal Management System, 7, 4-B, 2020, 599-605. doi: 10.21608/adjg.2020.23227.1229
Zakeer, S., Al.Ahmady, H., Adly, N., Zidan, A., Abd Alzeem, A. (2020). 'Effect of Mesenchymal Stem Cell Injection on Healing Outcome in Secondary Cleft Lip Correction', EKB Journal Management System, 7(4-B), pp. 599-605. doi: 10.21608/adjg.2020.23227.1229
Zakeer, S., Al.Ahmady, H., Adly, N., Zidan, A., Abd Alzeem, A. Effect of Mesenchymal Stem Cell Injection on Healing Outcome in Secondary Cleft Lip Correction. EKB Journal Management System, 2020; 7(4-B): 599-605. doi: 10.21608/adjg.2020.23227.1229

Effect of Mesenchymal Stem Cell Injection on Healing Outcome in Secondary Cleft Lip Correction

Al-Azhar Dental Journal for Girls
Article 7, Volume 7, 4-B, October 2020, Page 599-605  XML PDF (720.98 K)
Document Type: Original Article
DOI: 10.21608/adjg.2020.23227.1229
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Authors
Somaya M. Zakeer email 1; Hatem H. Al.Ahmady2; Nahed M. Adly3; Ahmed M. Zidan4; ahmed F. Abd Alzeem5
1Demonstrator at Oral and Maxillofacial Surgery Department, Faculty of Oral and Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.
2Professors of Oral and Maxillofacial Surgery, Faculty of Oral and Dental medicine for Girls, Al-Azhar University, Cairo, Egypt.
3Lecturer of Oral and Maxillofacial Surgery, Faculty of Oral and Dental medicine for Girls, Al-Azhar University, Cairo, Egypt.
4Lecturer of Diagnostic Radiology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
5Assistant researcher at Orodental Genetics Department, Human Genetic Division, National Research Center, Cairo, Egypt.
Abstract
Purpose: This study aimed to evaluate the effect of intraoperative mesenchymal stem cell injection on healing outcome in secondary cleft lip correction. Patients and Methods: A total of ten patients with secondary cleft lip deformities who needed secondary cleft lip repair were included in this study. The patients were divided equally into two groups: group I (study group) were subjected to secondary cleft lip repair with immediate intraoperative bone marrow mesenchymal stem cells injection (BM-MSCs), group Ⅱ (control group) who didn’t receive any type of injection neither during surgery nor after. The healing out come and scar progression were recorded through photographs and Ultrasonography (US). Results: Group I showed higher rate in primary healing outcome than that of group Ⅱ. The Ultrasound revealed statistically significant difference in scar progression in both groups. Group I showed statistically significant difference in scar measurements across time than group Ⅱ in p < 0.01. Conclusion: Bone marrow mesenchymal stem cell injection in cleft lip correction has a good effect on primary healing outcome and scar progression.
Keywords
Bone Marrow Mesenchymal Stem Cell; Ultrasonography
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