Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou
Abasse, O., Boukaré, K., Sampo, E., Bouda, R., CISSE, H., Stéphane, K., Odetokun, I., Sawadogo, A., Henri Nestor, B., SAVADOGO, A. (2022). Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou. EKB Journal Management System, 3(2), 318-331. doi: 10.21608/mid.2021.72261.1143
Ouédraogo Ganamé Abasse; Kaboré Boukaré; Emmanuel Sampo; Rober Bouda; Hama CISSE; Kpoda Dissinviel Stéphane; Ismail Odetokun; Adama Sawadogo; Bassolé Imael Henri Nestor; Aly SAVADOGO. "Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou". EKB Journal Management System, 3, 2, 2022, 318-331. doi: 10.21608/mid.2021.72261.1143
Abasse, O., Boukaré, K., Sampo, E., Bouda, R., CISSE, H., Stéphane, K., Odetokun, I., Sawadogo, A., Henri Nestor, B., SAVADOGO, A. (2022). 'Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou', EKB Journal Management System, 3(2), pp. 318-331. doi: 10.21608/mid.2021.72261.1143
Abasse, O., Boukaré, K., Sampo, E., Bouda, R., CISSE, H., Stéphane, K., Odetokun, I., Sawadogo, A., Henri Nestor, B., SAVADOGO, A. Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou. EKB Journal Management System, 2022; 3(2): 318-331. doi: 10.21608/mid.2021.72261.1143

Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou

Microbes and Infectious Diseases
Article 11, Volume 3, Issue 2, May 2022, Page 318-331  XML PDF (786.22 K)
Document Type: Original Article
DOI: 10.21608/mid.2021.72261.1143
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Authors
Ouédraogo Ganamé Abasseorcid 1; Kaboré Boukaré1; Emmanuel Sampo2; Rober Bouda3; Hama CISSEorcid 1; Kpoda Dissinviel Stéphane4; Ismail Odetokunorcid 5; Adama Sawadogoorcid 1; Bassolé Imael Henri Nestor6; Aly SAVADOGO email orcid 1
1Laboratory of Applied Biochemistry and Immunology, University Joseph Ki-ZERBO, Burkina Faso
2CSPS of Schiphra, Burkina Faso
3National Office of Water and Sanitation, Burkina Faso
4University of Ziniaré, Burkina Faso
5Department of Veterinary Public Health and Preventive Medicine, University of Ilorin, Nigeria
6Laboratory of Epidemiology and Surveillance of Foodborne Diseases, University Joseph Ki-ZERBO, Burkina Faso
Abstract
Background: The discharge of improperly treated hospital landfill presents an enormous public health risk. In Burkina Faso, the management of hospital’s wastewaters and the current antibiotic susceptibility of clinically relevant isolates need to be determined, because the multi-drug resistant isolates have been previously described in hospital settings. The aim of this study was to determine antibiotic resistance profile of isolates circulating in Ouagadougou.
Methods: The biochemical characterization of the isolates was carried out by tests from the API 20E test and completed with molecular characterization by simple PCR. Antibiotic susceptibility of the isolates was determined using the recommendations of CA-SFM 2019.
Results: The hospital wastewaters do not undergo any treatment before been discharged into the environment. A total of 171 presumed isolates of Salmonella spp < /em>, Pseudomonas spp < /em>., and Escherichia coli were identified in this study. These isolates derived from environment (n=19) and clinical (n=152). These isolates were resistant to Amoxicillin + clavulanic acid (95.32%), Cefoxitin (72.51%), Ceftazidime (78.94%), Cefepime (80.71%), Tobramycin (59.64%), Gentamicin (42.10%), Nalidixic acid (68.42%), Norfloxacin (59.06%), Ciprofloxacin (56.14%), imipenem (0.00%), Chloramphenicol (26.31%), and Colistin (77.77%). Somewhere else, 46 presumptive Staphylococcus aureus were resistant to Vancomycin (30.43%), Oxacillin (13.04%), Penicillin G (89.13%), Ceftriaxone (15.21%), Cefoxitin (2.73%), Tobramycin (36.95%), Kanamycin (30.43%), Ciprofloxacin (15.21%), Norfloxacin (43.47%), Tetracycline (56.52%), Chloramphenicol (13.04%), and Fosfomycin (2.73%). 
Conclusion: the hospital wastewaters harbour a variety of pathogens, most of which are resistant to several families of antibiotics.
Keywords
Multi-drug resistance; Antibiotics; Effluent; Hospital; Ouagadougou
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