PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS CHANGES IN DIABETIC PATIENTS AFTER PANRETINAL PHOTOCOAGULATION
K., T., M., M., M., E., Kh., S. (2021). PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS CHANGES IN DIABETIC PATIENTS AFTER PANRETINAL PHOTOCOAGULATION. EKB Journal Management System, 4(1), 15-22. doi: 10.21608/ejco.2021.189054
Tamam, K.; Mohamed, M.; Elmoddather, M.; Sayed, Kh.. "PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS CHANGES IN DIABETIC PATIENTS AFTER PANRETINAL PHOTOCOAGULATION". EKB Journal Management System, 4, 1, 2021, 15-22. doi: 10.21608/ejco.2021.189054
K., T., M., M., M., E., Kh., S. (2021). 'PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS CHANGES IN DIABETIC PATIENTS AFTER PANRETINAL PHOTOCOAGULATION', EKB Journal Management System, 4(1), pp. 15-22. doi: 10.21608/ejco.2021.189054
K., T., M., M., M., E., Kh., S. PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS CHANGES IN DIABETIC PATIENTS AFTER PANRETINAL PHOTOCOAGULATION. EKB Journal Management System, 2021; 4(1): 15-22. doi: 10.21608/ejco.2021.189054

PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS CHANGES IN DIABETIC PATIENTS AFTER PANRETINAL PHOTOCOAGULATION

Egyptian Journal of Clinical Ophthalmology
Article 2, Volume 4, Issue 1, June 2021, Page 15-22  XML PDF (409.53 K)
Document Type: Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations
DOI: 10.21608/ejco.2021.189054
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Authors
Tamam, K.1; Mohamed, M.1; Elmoddather, M.1; Sayed, Kh.2
1Ophthalmology dept., Faculty of Medicine, AL-Azhar Univ., Assuit, Egypt
2Ophthalmology dept., Faculty of Medicine, Sohag Univ., Sohag, Egypt
Abstract
Aim of the work: This study aimed to assess the effect of Panretinal photocoagulation (PRP) on the peripapillary Retinal Nerve Fiber (RNFL) thickness in diabetic patients using Optical Coherence Tomography Angiography. Methods: A prospective study was conducted on 100 eyes of 62 patients who had severe non-proliferative (SNPDR) or proliferative diabetic retinopathy (PDR) and underwent PRP treatment. The study population underwent 4.5×4.5 MM scans centered on the optic nerve head using Optical Coherence Tomography Angiography (OCTA) (RTVue XR Avanti Optovue, Fremont, CA) for measuring the peripapillary RNFL thickness before and after PRP by 2 months and 6 months. Results: Mean age of the study population was 49.85± 8.26 years (25-64 years). There was a significant increase in thickness of the nasal, temporal, superior and inferior peripapillary RNFL from baseline to 2 months post-PRP (all P value <0.05) and then decreased significantly from 2 months to 6 months (all P value <0.05). However, the thickness decreased significantly to amount less than baseline after 6 months for superior and inferior quadrants (P value <0.05) and decreased insignificantly for nasal and temporal quadrants (P value > 0.05). Conclusions: Peripapillary RNFL thickness at 6 months has decreased post-PRP, suggesting that PRP had neuronal insult.
Keywords
Diabetic retinopathy; proliferative; photocoagulation; Optical Coherence; Angiography
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