Chemical Composition and Biological Activities of The Essential Oil Of Pulicaria Crispa In The Middle East
Dekinash, M., Beltagy, A., El Naggar, E., Khattab, A., El Fiky, F. (2018). Chemical Composition and Biological Activities of The Essential Oil Of Pulicaria Crispa In The Middle East. EKB Journal Management System, 1(1), 16-34. doi: 10.21608/dusj.2018.205304
Mohamed F. Dekinash; Amira M. Beltagy; El Moataz Bellah A. El Naggar; Amira R. Khattab; Fathy K. El Fiky. "Chemical Composition and Biological Activities of The Essential Oil Of Pulicaria Crispa In The Middle East". EKB Journal Management System, 1, 1, 2018, 16-34. doi: 10.21608/dusj.2018.205304
Dekinash, M., Beltagy, A., El Naggar, E., Khattab, A., El Fiky, F. (2018). 'Chemical Composition and Biological Activities of The Essential Oil Of Pulicaria Crispa In The Middle East', EKB Journal Management System, 1(1), pp. 16-34. doi: 10.21608/dusj.2018.205304
Dekinash, M., Beltagy, A., El Naggar, E., Khattab, A., El Fiky, F. Chemical Composition and Biological Activities of The Essential Oil Of Pulicaria Crispa In The Middle East. EKB Journal Management System, 2018; 1(1): 16-34. doi: 10.21608/dusj.2018.205304

Chemical Composition and Biological Activities of The Essential Oil Of Pulicaria Crispa In The Middle East

Delta University Scientific Journal
Article 3, Volume 1, Issue 1, 2018, Page 16-34  XML PDF (1.66 MB)
Document Type: Review articles
DOI: 10.21608/dusj.2018.205304
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Authors
Mohamed F. Dekinash1; Amira M. Beltagy1; El Moataz Bellah A. El Naggar1; Amira R. Khattab2; Fathy K. El Fiky3
1Department of Pharmacognosy, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt
2Division of Pharmaceutical Sciences, Department of Pharmacognosy, College of Arab Academy for Science, Technology and Maritime Transport, Alexandria, Egypt
3Department of Pharmacognosy, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa , Egypt.
Abstract
Pulicaria crispa, family Compositae is an annual herb, locally known as gethgath. The plant was reported to be used in Saudi Arabia on bruises, skin infections and gastrointestinal disturbances due to its essential oil content. It has been used from ancient times in the treatment of sinusitis and respiratory tract infections in the traditional medicine system in southern Iran. Many studies have been conducted on P. crispa essential oil in many countries in the middle east; the essential oil of P. crispa was found to be characterized by changes in the chemotype due to various factors including for example: the part of the plant used, stage of plant development, genetic factors, the environmental conditions, the harvest period and the nature of the soil. The oil showed antibacterial, sedative, antioxidant activity and cytotoxic activity. Moreover, the oil was reported to possess a good anticancer efficacy against human colorectal adenocarcinoma (Caco-2) and a slightly lower anticancer efficacy against hepatocellular cancer cell line (HepG-2).
Keywords
Pulicaria crispa; essential oil; composition; GC-MS; biological activity
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