Effect of Tarragon (Artemisia dracunculus L.) and Its Ethanolic Extracts on Chronic Liver Disease in Male Albino Rats
A. Ismail, E., S. Abdalla, E., F. Khalil, A., M. El-Hadidy, E. (2021). Effect of Tarragon (Artemisia dracunculus L.) and Its Ethanolic Extracts on Chronic Liver Disease in Male Albino Rats. EKB Journal Management System, 2(2), 46-59. doi: 10.21608/ijfsnh.2021.209199
Eman A. Ismail; Eveleen S. Abdalla; Ayman F. Khalil; Eshak M. El-Hadidy. "Effect of Tarragon (Artemisia dracunculus L.) and Its Ethanolic Extracts on Chronic Liver Disease in Male Albino Rats". EKB Journal Management System, 2, 2, 2021, 46-59. doi: 10.21608/ijfsnh.2021.209199
A. Ismail, E., S. Abdalla, E., F. Khalil, A., M. El-Hadidy, E. (2021). 'Effect of Tarragon (Artemisia dracunculus L.) and Its Ethanolic Extracts on Chronic Liver Disease in Male Albino Rats', EKB Journal Management System, 2(2), pp. 46-59. doi: 10.21608/ijfsnh.2021.209199
A. Ismail, E., S. Abdalla, E., F. Khalil, A., M. El-Hadidy, E. Effect of Tarragon (Artemisia dracunculus L.) and Its Ethanolic Extracts on Chronic Liver Disease in Male Albino Rats. EKB Journal Management System, 2021; 2(2): 46-59. doi: 10.21608/ijfsnh.2021.209199

Effect of Tarragon (Artemisia dracunculus L.) and Its Ethanolic Extracts on Chronic Liver Disease in Male Albino Rats

International Journal of Family Studies, Food Science and Nutrition Health
Volume 2, Issue 2, December 2021, Page 46-59  XML PDF (1.79 MB)
Document Type: Original Research
DOI: 10.21608/ijfsnh.2021.209199
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Authors
Eman A. Ismail1; Eveleen S. Abdalla1; Ayman F. Khalil1; Eshak M. El-Hadidy2
1Home Economics Dept., Faculty of Specific Education, Ain Shams Univ., Egypt
2Agricultural Research Center, Food Technology Research Institute, Egypt
Abstract
Tarragon (Artemisia dracunculus L.) is a herb belonging to the Asteraceae family with a long 
history of protective effect and other medicinal benefits. This study aiming for studying Effect of 
Tarragon dried leaves and its ethanolic extracts (80%) at different concentrations on chronic liver 
disease. Result of chemical composition of dried tarragon leaves (protein, carbohydrates, oil, fiber 
and ash (23.42, 48.53, 6.99 and 7.03 g/100g, respectively) .It is rich in polyphenol, flavonoids and
carotenoids contents (28.5, 15.45 and 9.98 mg/100g, respectively). Antioxidants activity in dried of 
tarragon leaves was high(86.43%) the major phenolic compounds were Benzoic acid, Catechein, 
Salycillic acid and Pyrogallol (1405.42, 8080.80, 252.71 and 213.25ppm, respectively). Also, 
flavonoids fractions indicated the highest content in Acacetin neo.rutinoside, Apig.6-arbinose8-
glactose, Apegnin, Luteolin 7-glucose and Hespirtin (907.70; 609.15; 576.54; 361.49 and 307.31 
ppm, respectively). Sixty male albino rats weighted (180±20g) were fed on basal diet for two weeks 
before the experiment were divided to ten main groups for 60 days as follows: G1 (normal) and G2
induced CCl4, in paraffin oil (50% v/v 2ml/Kg) twice weeks for chronic damage rats of liver rats and 
fed on basal diet. ( G3 normal and G4 induced CCl4) fed on diet containing tarragon powder 1%
,(G5 normal, and G6 induced CCl4) fed on diet containing tarragon powder 2% ,(G7 normal and G8
induced CCl4) treated orally with(100mg/Kg wt./day) tarragon extract. (G9 normal, G10 induced
CCl4) treated with 200mg/kg wt./day tarragon extract, orally . At the end of the experimental, 
serums were collected for determine liver and kidney functions. Results showed that decreased in 
AST , ALT and ALP in groups (9 and 10) which had oral tarragon extract (100 and 200mg /kg), while
uric acid increased in G10 (47.67mg/dL), but was decreased creatinine in G6 (0.55mg/dL) which had 
taken 2% tarragon powder. Conclusively, tarragon extracts were significantly improved hepatorenal serum parameters in chronic liver disease rats groups. 
Keywords
Tarragon (Artemisia dracunculus L); Dried Leaves; Polyphenols; Flavonoids; Chronic Liver Disease
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