Comparative Study of TI-RADS, Elasticity Score, Strain Ratio and Quantitative Diffusion MR Weighted Imaging in Characterization of Thyroid Nodules; Which Has the Best Diagnostic performance? | ||||
| SVU-International Journal of Medical Sciences | ||||
| Article 16, Volume 5, Issue 2, July 2022, Page 159-172 PDF (530.93 K) | ||||
| Document Type: Original research articles | ||||
| DOI: 10.21608/svuijm.2022.127300.1294 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed M. Magdy   ; Ahmed Adel Mahmoud; Ashraf Talaat Youssef
| ||||
| Department of Diagnostic Radiology, Faculty of Medicine, Fayoum University, Fayoum, Egypt | ||||
| Abstract | ||||
| Background: Thyroid nodules are common disorder of the thyroid gland. Early and precise diagnosis of malignant thyroid nodules is fundamental for effective treatment. Objectives: The purpose of this study is comparative evaluation of the diagnostic performance of TI-RADS, elasticity score, strain ratio and quantitative diffusion-weighted MRI in characterization of malignant and benign thyroid nodules. Patients and methods: Our study is prospective. 59 patients with 59 thyroid nodules were enrolled in this study. Conventional ultrasound with TI-RADS categorization, ultrasound strain elastography (elasticity score and strain ratio) as well as diffusion-weighted MR imaging and ADC value were evaluated for all cases. Histopathology results were the standard reference. Results: TI-RADS score had (80 %) sensitivity, (89.8 %) specificity and (84.9 %) accuracy. Elasticity score using 4-points Asteria's criteria with cutoff value =3 had (70 %) sensitivity, (91.8 %) specificity and (80.9 %) accuracy. When a cutoff value of 1.65 was used for strain ratio; (90 %) sensitivity, (71.4 %) specificity and (91.8 %) diagnostic accuracy noted. When a cutoff value of 1.45 x10-3 was used for ADC value; (80 %) sensitivity, (95.9 %) specificity and overall accuracy (98%) noticed. Multiparametric analysis enhanced the overall accuracy of TI-RADS scoring with the best diagnostic performance was achieved in our study by combining diffusion ADC value to the TI-RADS scoring with sensitivity 100%, specificity 95.9% and accuracy 98%. Conclusions: Strain ratio and diffusion ADC value had higher diagnostic performance than US TI-RADS scoring in characterizing thyroid nodules. The best diagnostic performance in our study was achieved by combining diffusion ADC value to the TI-RADS scoring with overall accuracy of about 98%. | ||||
| Keywords | ||||
| Thyroid nodules; strain elastography; diffusion; TI-RADS; ADC | ||||
|
Statistics Article View: 237 PDF Download: 194 |
||||
