Antibacterial effect of rhodanine derivatives against bacteria isolated from the River Nile, Egypt | ||||
Egyptian Journal of Aquatic Biology and Fisheries | ||||
Article 67, Volume 26, Issue 5, September and October 2022, Page 1229-1239 PDF (511.8 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejabf.2022.268264 | ||||
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Author | ||||
Saleh Ahmed Rabeh | ||||
Abstract | ||||
The objectives of the present study were to isolate and identify some pathogenic bacteria from the River Nile water and to evaluate the rhodanine derivatives as potent antibacterial agents. The results showed that rhodanine derivatives No. 7c and 8 were the most effective against all tested bacteria. On the other hand, rhodanine derivatives, No. 2a,2b, 2c, and 9b have no antibacterial activities against pathogenic Gram-positive and Gram-negative bacteria, while the other derivatives exhibited either low or moderate antibacterial activities against some of the tested bacteria. Therefore, it was suggested that rhodanine derivatives are promising as novel antibacterial agents for pharmaceutical applications, water treatment and preventing and controlling fish diseases in aquaculture. | ||||
Keywords | ||||
River Nile; Pathogenic bacteria; Rhodanine derivatives; Antibacterial agent | ||||
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